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Anti-Nuclear Antibody (ANA) ELISA 试剂盒

ANA 适用: 人 Colorimetric Sandwich ELISA
产品编号 ABIN930744
发货至: 中国
  • 抗原 See all Anti-Nuclear Antibody (ANA) ELISA试剂盒
    Anti-Nuclear Antibody (ANA)
    适用
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    Analytical Method
    Qualitative
    产品特性
    ELISA kit for the detection of ANA in the research laboratory
    Alternative Names: Anti-nuclear antibodies ELISA kit
    Top Product
    Discover our top product ANA ELISA Kit
  • 应用备注
    Optimal conditions to be determined by end-user
    板类型
    Pre-coated
    实验流程

    ANA Detect ELISA is an indirect solid phase enzyme immunoassay (ELISA) for the detection of antinuclear antibodies (ANAs) in human serum. Specifically purified autoantigens SSA52 (Ro 52), SSA60 (Ro 60), SSB (La), RNP/Sm, RNP70 Kd, RNPA, RNPC, SmBB, SmD, SmE, SmF, SmG, Scl70, Jo1, dsDNA, ssDNA, polynucleosomes, mononucleosomes, Histonecomplex, Histone H1, Histone H2A, Histone H2B, Histone H3, Histone H4, PMScl100, Centromere B are coated onto the microwells of a 96well microplate which can be divided into 12 modules of 8 wells each.

    限制
    仅限研究用
  • 储存条件
    4 °C
    储存方法
    Store at 2-8 °C.
  • 抗原 See all Anti-Nuclear Antibody (ANA) ELISA试剂盒
    Anti-Nuclear Antibody (ANA)
    别名
    anti-ANA (ANA 产品)
    物质类
    Antibody, Antibody
    背景
    Inflammatory connective tissue diseases are characterized by idiopathic genesis along with disturbances in terms of cellular and humoral immunity, systemic organ failure and a chronic course of disease. Additionally, connective tissue diseases exhibit overlapping symptomatic features that render an accurate diagnosis difficult. Considering the diversity of mixed connective tissue diseases, such disorders exhibit a common serological characteristic, the presence of antinuclear antibodies. These antibodies are directed against parts of the cell nucleus and the cytoplasm, and many rheumatic diseases are characterized by the presence of one or more of these ANAs. Antibodies to doublestranded DNA (dsDNA), singlestranded DNA (ssDNA), histone, nuclear ribonucleoprotein (RNP) and Smith antigen (Sm) are associated with SLE, while antibodies to Sjogren´s Syndrome A (SSA/Ro) and Sjogren´s Syndrome B (SSB/La) can occur in both SLE and Sjogren´s Syndrome (SS). Antibodies to Jo1 may be observed in polymyositis and dermatomyositis, while antibodies to sclerodermaassociated antigen (Scl70) and centromere can occur in patients with progressive systemic sclerosis (PSS). Antihistone antibodies are associated with SLE and druginduced lupus, while antiRNP antibodies are linked with mixed connective tissue disease (MCTD) and with SLE. Antibodies directed against centromere are associated with CREST syndrome.
    Synonyms: Anti-nuclear antibodies ELISA kit.
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