FURIN ELISA 试剂盒
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- 抗原 See all FURIN ELISA试剂盒
- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 312 pg/mL - 20000 pg/mL
- 最低检测浓度
- 312 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Lysate, Cell Culture Supernatant, Tissue Homogenate
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: Dibasic processing enzyme, Dibasic-processing enzyme, FES upstream region, FUR, FURIN, Furin membrane associated receptor protein, FURIN_HUMAN, PACE, Paired basic amino acid residue cleaving enzyme, Paired basic amino acid residue-cleaving enzyme, PCSK3, Proprotein convertase subtilisin/kexin type 3, SPC1
Background: Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The FUR gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance
Gene Name: FURIN
Production: Natural and recombinant human Furin. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: D108-E715
- Top Product
- Discover our top product FURIN ELISA Kit
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 20000pg/mL, 10000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL human Furin standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, tissue homogenates or cell lysates to each empty well. It is recommended that each human Furin standard solution and each sample be measured in duplicate.
ELISA Dilution: 312pg/mL-20000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- 抗原 See all FURIN ELISA试剂盒
- FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
- 别名
- Furin (FURIN 产品)
- 别名
- FURIN ELISA Kit, furin ELISA Kit, si:dkey-281a24.5 ELISA Kit, FUR ELISA Kit, LOC100220259 ELISA Kit, PACE ELISA Kit, spc1 ELISA Kit, xfurin ELISA Kit, MGC82710 ELISA Kit, PCSK3 ELISA Kit, SPC1 ELISA Kit, 9130404I01Rik ELISA Kit, Fur ELISA Kit, Pcsk3 ELISA Kit, Pace ELISA Kit, furin, paired basic amino acid cleaving enzyme ELISA Kit, furin (paired basic amino acid cleaving enzyme) a ELISA Kit, furin (paired basic amino acid cleaving enzyme) b ELISA Kit, furin, paired basic amino acid cleaving enzyme L homeolog ELISA Kit, furin (paired basic amino acid cleaving enzyme) ELISA Kit, FURIN ELISA Kit, furina ELISA Kit, furinb ELISA Kit, furin ELISA Kit, furin.L ELISA Kit, Furin ELISA Kit
- 基因ID
- 5045
- NCBI登录号
- NP_001276752
- UniProt
- P09958
- 途径
- Notch Signaling, Neurotrophin Signaling Pathway
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