IL18BP ELISA 试剂盒
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- 抗原 See all IL18BP ELISA试剂盒
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 93.7 pg/mL - 6000 pg/mL
- 最低检测浓度
- 93.7 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Urine
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: I18BP_HUMAN, IL-18BP, IL18BP, Interleukin-18-binding protein, Tadekinig-alfa
Background: Interleukin-18-binding protein, also known as IL18BPa, is a protein that in humans is encoded by the IL18BP gene. It is mapped to 11q13.4. The protein encoded by this gene is an inhibitor of the proinflammatory cytokine IL18. This protein binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. This protein is constitutively expressed and secreted in mononuclear cells. The expression of this protein can be enhanced by IFN-gamma. It has been found that IL18BP expression in intestinal tissue is increased in endothelial cells as well as cells of the submucosa and overlying lymphoid aggregates in Crohn disease.
Gene Name: IL18BP
Production: Natural and recombinant human IL-18BP. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: T31-G194
- Top Product
- Discover our top product IL18BP ELISA Kit
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 6000pg/mL, 3000pg/mL, 1500pg/mL, 750pg/mL, 419pg/mL, 187.5pg/mL, 93.7pg/m human IL-18BP standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA) or urine to each empty well. It is recommended that each human IL-18BP standard solution and each sample be measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 93.7pg/mL-6000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- 抗原 See all IL18BP ELISA试剂盒
- IL18BP (Interleukin 18 Binding Protein (IL18BP))
- 别名
- IL-18BP (IL18BP 产品)
- 别名
- IL18BP ELISA Kit, IL-18BP ELISA Kit, Igifbp ELISA Kit, MC54L ELISA Kit, IL18BPa ELISA Kit, interleukin 18 binding protein ELISA Kit, IL18BP ELISA Kit, Il18bp ELISA Kit
- 基因ID
- 10068
- NCBI登录号
- NP_001034748
- UniProt
- O95998
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