DLL4 ELISA 试剂盒
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- 抗原 See all DLL4 ELISA试剂盒
- DLL4 (delta-Like 4 (DLL4))
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适用
- 小鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 156 pg/mL - 10000 pg/mL
- 最低检测浓度
- 156 pg/mL
- 应用范围
- ELISA
- Supplier Product No.
- koa0753
- Supplier
- Rockland
- 原理
- Mouse DLL4 Sandwich ELISA Kit for Quantitative Detection
- 品牌
- AccuSignal™
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- 特异性
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Production: Natural and recombinant mouse DLL4. There is no detectable cross-reactivity with other relevant proteins.
- 灵敏度
- < 10 pg/mL
- 组件
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- Antibody-coated 96-well plate
- Target Protein Standard
- Detection antibody
- Detection reagent
- Diluent buffers
- Wash buffers
- Substrate Solution
- Stop solutions
- Adhesive covers
- Featured
- Discover our best selling DLL4 ELISA Kit
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- Discover our top product DLL4 ELISA Kit
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delta-Like 4 (DLL4) ELISA Kit
DLL4 适用: 人 Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
delta-Like 4 (DLL4) ELISA KitDLL4 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate
delta-Like 4 (DLL4) ELISA KitDLL4 适用: 大鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Tissue Homogenate
delta-Like 4 (DLL4) ELISA KitDLL4 适用: 小鼠 AA 28-525 Colorimetric Sandwich ELISA 156-10.000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
delta-Like 4 (DLL4) ELISA KitDLL4 适用: 大鼠 AA 28-519 Colorimetric Sandwich ELISA
delta-Like 4 (DLL4) ELISA KitDLL4 适用: 大鼠 Colorimetric Sandwich ELISA 0.156 ng/mL - 10 ng/mL Tissue Homogenate
delta-Like 4 (DLL4) ELISA KitDLL4 适用: 小鼠 Colorimetric Sandwich ELISA 156-10000 pg/mL Cell Culture Supernatant, Plasma, Serum
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- 应用备注
- Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL mouse DLL4 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernates, serum or plasma(heparin, EDTA) to each empty well. It is recommended that each mouse DLL4 standard solution and each sample be measured in duplicate.
- 说明
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Standard: Expression system for standard: NSO, Immunogen sequence: S28-P525
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
- 有效期
- 12 months
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- 抗原 See all DLL4 ELISA试剂盒
- DLL4 (delta-Like 4 (DLL4))
- 别名
- DLL4 (DLL4 产品)
- 背景
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Synonyms: Delta 4, delta 4 precursor, Delta ligand 4, delta ligand 4 precursor, Delta like 4, Delta like 4 homolog, Delta like 4 protein, Delta like protein 4, Delta-like 4 (Drosophila), Delta-like protein 4, Delta4, DLL 4, DLL4, DLL4_HUMAN, Drosophila Delta homolog 4, hdelta2, Homeobox protein DLL-4, MGC126344, Notch ligand delta 2, Notch ligand DLL4, notch ligand DLL4 precursor, XDLL-4
Background: Delta like ligand 4 is a protein that in humans is encoded by the DLL4 gene. It is mapped to 15q15.1. This gene is a homolog of the Drosophila delta gene. DLL4 is a transmembrane ligand for Notch receptors that shows restricted expression to endothelial cells (ECs), in particular to arteries and capillaries, and is involved in vascular development, and it also appeared to be a major trigger of Notch receptor activities previously implicated in arterial and vascular development. Mouse DLL4 could activate mouse Notch1 and mouse Notch4. DLL4 acts as a negative regulator of tumor angiogenesis, its blockade results in the striking uncoupling of tumor growth from vessel density, presenting a novel therapeutic approach even for tumors resistant to anti-VEGF therapies. In addition to it, this gene also plays an important role in promoting Th17 effector activity during mycobacterial challenge.
- 基因ID
- 54485
- NCBI登录号
- NP_062327
- UniProt
- Q9JI71
- 途径
- Notch Signaling
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