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PLAUR ELISA 试剂盒

PLAUR 适用: 人 Colorimetric Sandwich ELISA 62.5 pg/mL - 4000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
产品编号 ABIN6719976
发货至: 中国
  • 抗原 See all PLAUR ELISA试剂盒
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    适用
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    62.5 pg/mL - 4000 pg/mL
    最低检测浓度
    62.5 pg/mL
    应用范围
    ELISA
    原理
    Sandwich ELISA for Quantitative Detection of Antigen
    样品类型
    Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
    Analytical Method
    Quantitative
    产品特性

    Synonyms: CD87, Monocyte activation antigen Mo3, PLAUR, U-PAR, uPAR, UPAR_HUMAN, Urokinase plasminogen activator surface receptor

    Background: The urokinase-type plasminogen activator receptor(uPAR) is a key molecule in the regulation of cell-surface plasminogen activation and, as such, plays an important role in many normal as well as pathological processes. The cDNA for Mo3, an activation antigen expressed by human monocytes and myelomonocytic cell lines after stimulation by a variety of agents. Mo3 expression in vivo is associated predominantly with macrophages in inflammatory sites. It is a highly glycosylated protein of about 50 kD in monocytes where it is anchored to the plasma membrane by glycosyl-phosphatidylinositol linkage. The complete coding sequence of the cDNA has been found to encode 419 amino acids including a predicted signal peptide of 22 residues and a hydrophobic C-terminal portion. Mo3 is identical to the human receptor for the urokinase plasminogen activator. UPAR is a useful prognostic marker for biologically aggressive forms of endometrial cancer. PLAUR is located at chromosome 19q13.1-q13.2. The standard product used in this kit is recombinant human uPAR, consisting of 287 amino acids with the molecular mass of 31KDa.

    Gene Name: PLAUR

    Production: Natural and recombinant human Upar. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: L23-R303

    Top Product
    Discover our top product PLAUR ELISA Kit
  • 应用备注

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 4000pg/mL, 2000pg/mL, 1000pg/mL, 500pg/mL, 250pg/mL, 125pg/mL, 62.5pg/mL human uPAR standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, serum, plasma(heparin, EDTA) or urine to each empty well. We recommend that each human uPAR standard solution and each sample is measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 62.5pg/mL-4000pg/mL

    样本量
    100 μL
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • 抗原 See all PLAUR ELISA试剂盒
    PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))
    别名
    uPAR (PLAUR 产品)
    别名
    Cd87 ELISA Kit, u-PAR ELISA Kit, uPAR ELISA Kit, CD87 ELISA Kit, U-PAR ELISA Kit, UPAR ELISA Kit, URKR ELISA Kit, Par ELISA Kit, Plaur3 ELISA Kit, uPAR-2 ELISA Kit, uPAR-3 ELISA Kit, PLAUR ELISA Kit, plasminogen activator, urokinase receptor ELISA Kit, Plaur ELISA Kit, PLAUR ELISA Kit
    基因ID
    5329
    NCBI登录号
    NP_001005376
    UniProt
    Q03405
    途径
    Inositol Metabolic Process
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