NRP2 ELISA 试剂盒
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- 抗原 See all NRP2 ELISA试剂盒
- NRP2 (Neuropilin 2 (NRP2))
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适用
- 大鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 156 pg/mL - 10000 pg/mL
- 最低检测浓度
- 156 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Lysate, Cell Culture Supernatant, Tissue Homogenate
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: MGC126574, Neuropilin 2, Neuropilin-2, Neuropilin2, NP 2, NP2, NPN 2, NPN2, NRP 2, Nrp2, NRP2_HUMAN, PRO2714, Receptor for VEGF165 and semaphorins class3, Vascular endothelial cell growth factor 165 receptor 2, Vascular endothelial growth factor 165 receptor 2, VEGF1265R2, VEGF165R2
Background: NRP2(Neuropilin-2), also called Npn2 or VEGF165R2, encodes a member of the neuropilin family of receptor proteins. The soluble NRP2 was secreted as a 62.5-kD protein following transfection in Chinese hamster ovary cells. The NRP2 gene is mapped to 2q33.3. The NRP2 gene contains 17 exons and spans about 112 kb. This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Mice with null mutations in genes encoding Sema3F, and its holoreceptor components Npn2 and plexin A3 (PLEXA3), exhibit increased dentate gyrus granule cell and cortical layer V pyramidal neuron spine number and size, and also aberrant spine distribution. Moreover, Sema3F promotes loss of spines and excitatory synapses in dissociated neurons in vitro, and in NRP2-null brain slices cortical layer V and dentate gyrus granule cells exhibit increased miniature excitatory postsynaptic current frequency. These disparate effects of secreted semaphorins are reflected in the restricted dendritic localization of NRP2 to ...
Gene Name: NRP2
Production: Natural and recombinant rat Neuropilin-2. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: Q23-D857
- Top Product
- Discover our top product NRP2 ELISA Kit
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 10,000pg/mL, 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL rat Neuropilin-2 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of rat cell culture supernates, cell lysates or tissue homogenates to each empty well. It is recommended that each rat Neuropilin-2 standard solution and each sample be measured in duplicate.
ELISA Dilution: 156pg/mL-10,000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- 抗原 See all NRP2 ELISA试剂盒
- NRP2 (Neuropilin 2 (NRP2))
- 别名
- Neuropilin-2 (NRP2 产品)
- 别名
- NP2 ELISA Kit, NPN2 ELISA Kit, PRO2714 ELISA Kit, VEGF165R2 ELISA Kit, 1110048P06Rik ELISA Kit, Np-2 ELISA Kit, Np2 ELISA Kit, Npn-2 ELISA Kit, Npn2 ELISA Kit, neuropilin-2 ELISA Kit, neuropilin 2 ELISA Kit, NRP2 ELISA Kit, Nrp2 ELISA Kit
- 基因ID
- 81527
- NCBI登录号
- NP_110496
- UniProt
- O35276
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
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