RAGE ELISA 试剂盒
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- 抗原 See all RAGE (AGER) ELISA试剂盒
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
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适用
- 小鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 78 pg/mL - 5000 pg/mL
- 最低检测浓度
- 78 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: Advanced glycosylation end product specific receptor, Advanced glycosylation end product-specific receptor, Ager, DAMA 358M23.4, LE 9211 A antigen, MAPK MAK MRK overlapping kinase, MGC22357, MOK, OTTHUMP00000174885, RAGE 1, RAGE isoform NtRAGE-delta, RAGE isoform sRAGE-delta, RAGE_HUMAN, RAGE1, Receptor for advanced glycation end products, receptor for advanced glycation end-products variant 20, Receptor for advanced glycosylation end products, Renal tumor antigen, Renal tumor antigen 1
Background: RAGE, the Receptor for Advanced Glycation Endproducts, is a 35kD transmembrane receptor of the immunoglobulin super family. It is also known as ""AGER"". AGER gene is mapped to chromosome 6p21.3 by mapping by contiguous cosmids and YAC clones and by fluorescence in situ hybridization. The expression of RAGE is particularly increased in neurons close to deposits of amyloid beta peptide and to neurofibrillary tangles. RAGE has been linked to several chronic diseases, which are thought to result from vascular damage. The pathogenesis is hypothesized to include ligand binding upon which RAGE signals activation of the nuclear factor kappa B(NF-kappaB).
Gene Name: AGER
Production: Natural and recombinant mouse RAGE. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: Q24-A342
- Top Product
- Discover our top product AGER ELISA Kit
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL, 78pg/mL mouse RAGE standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of mouse cell culture supernatants, serum or plasma(heparin, EDTA) to each empty well. We recommend that each mouse RAGE standard solution and each sample is measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 78pg/mL-5000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
-
- 抗原 See all RAGE (AGER) ELISA试剂盒
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- 别名
- RAGE (AGER 产品)
- 别名
- RAGE ELISA Kit, AGER ELISA Kit, advanced glycosylation end-product specific receptor ELISA Kit, advanced glycosylation end product-specific receptor ELISA Kit, MAPK/MAK/MRK overlapping kinase ELISA Kit, AGER ELISA Kit, Ager ELISA Kit, LOC719012 ELISA Kit
- 基因ID
- 11596
- NCBI登录号
- NP_001258351
- UniProt
- Q62151
- 途径
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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