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Kallikrein 6 ELISA 试剂盒

KLK6 适用: 人 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Cell Culture Lysate, Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Tissue Homogenate
产品编号 ABIN6719698
发货至: 中国
  • 抗原 See all Kallikrein 6 (KLK6) ELISA试剂盒
    Kallikrein 6 (KLK6)
    适用
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    78 pg/mL - 5000 pg/mL
    最低检测浓度
    78 pg/mL
    应用范围
    ELISA
    原理
    Sandwich ELISA for Quantitative Detection of Antigen
    样品类型
    Cell Culture Lysate, Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Tissue Homogenate
    Analytical Method
    Quantitative
    产品特性

    Synonyms: Kallikrein-6, Klk6, KLK6_HUMAN, Neurosin, Protease M, Serine protease 18, Serine protease 9, SP59, Zyme

    Background: KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.

    Gene Name: KLK6

    Production: Natural and recombinant human Kallikrein-6. There is no detectable cross-reactivity with other relevant proteins.

    Standard: Expression system for standard: NSO, Immunogen sequence: L22-K244

    Top Product
    Discover our top product KLK6 ELISA Kit
  • 应用备注

    Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL, 78pg/mL human Kallikrein-6 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, cell lysates, serum, plasma(heparin, EDTA) or tissue homogenates to each empty well. We recommend that each human Kallikrein-6 standard solution and each sample is measured in duplicate.

    Blood Product Anticoagulant: Heparin Sodium

    ELISA Dilution: 78pg/mL-5000pg/mL

    样本量
    100 μL
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    RT,4 °C,-20 °C
    储存方法
    Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
  • 抗原 See all Kallikrein 6 (KLK6) ELISA试剂盒
    Kallikrein 6 (KLK6)
    别名
    Kallikrein-6 (KLK6 产品)
    别名
    Bssp ELISA Kit, Klk7 ELISA Kit, PRSS18 ELISA Kit, PRSS9 ELISA Kit, SP59 ELISA Kit, hK6 ELISA Kit, Prss9 ELISA Kit, AI849898 ELISA Kit, BSP ELISA Kit, Klk29 ELISA Kit, MSP ELISA Kit, Prss18 ELISA Kit, neurosin ELISA Kit, kallikrein related peptidase 6 ELISA Kit, kallikrein related-peptidase 6 ELISA Kit, kallikrein-6 ELISA Kit, KLK6 ELISA Kit, Klk6 ELISA Kit, LOC100716801 ELISA Kit
    基因ID
    5653
    NCBI登录号
    NP_001012982
    UniProt
    Q92876
    途径
    Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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