Kallikrein 6 ELISA 试剂盒
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- 抗原 See all Kallikrein 6 (KLK6) ELISA试剂盒
- Kallikrein 6 (KLK6)
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 78 pg/mL - 5000 pg/mL
- 最低检测浓度
- 78 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich ELISA for Quantitative Detection of Antigen
- 样品类型
- Cell Culture Lysate, Cell Culture Supernatant, Plasma (EDTA - heparin), Serum, Tissue Homogenate
- Analytical Method
- Quantitative
- 产品特性
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Synonyms: Kallikrein-6, Klk6, KLK6_HUMAN, Neurosin, Protease M, Serine protease 18, Serine protease 9, SP59, Zyme
Background: KLK6(Kallikrein-related peptidase 6), also called KALLIKREIN 6, NEUROSIN, PROTEASE M, ZYME or PRSS9, is a protein that in humans is encoded by the KLK6 gene. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. Northern blot analysis revealed that the PRSS9 mRNA was expressed in several primary tumors and cell lines from mammary, prostate, and ovarian cancers, but was not detected in any metastases of these cancers. The KLK6 gene is mapped on 19q13.41. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Upon cellular stress, neurosin was released from mitochondria to the cytosol, which resulted in the increase of degraded alpha-synuclein species. Neurosin may play a significant role in physiologic alpha-synuclein degradation and also in the pathogenesis of synucleinopathies.
Gene Name: KLK6
Production: Natural and recombinant human Kallikrein-6. There is no detectable cross-reactivity with other relevant proteins.
Standard: Expression system for standard: NSO, Immunogen sequence: L22-K244
- Top Product
- Discover our top product KLK6 ELISA Kit
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- 应用备注
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Application Note: Useful in Sandwich ELISA for Quantitative Detection of Antigen. Aliquot 0.1 mL per well of the 5000pg/mL, 2500pg/mL, 1250pg/mL, 625pg/mL, 312pg/mL, 156pg/mL, 78pg/mL human Kallikrein-6 standard solutions into the precoated 96-well plate. Add 0.1 mL of the sample diluent buffer into the control well (Zero well). Add 0.1 mL of each properly diluted sample of human cell culture supernates, cell lysates, serum, plasma(heparin, EDTA) or tissue homogenates to each empty well. We recommend that each human Kallikrein-6 standard solution and each sample is measured in duplicate.
Blood Product Anticoagulant: Heparin Sodium
ELISA Dilution: 78pg/mL-5000pg/mL
- 样本量
- 100 μL
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- RT,4 °C,-20 °C
- 储存方法
- Store vials at 4°C prior to opening. Centrifuge product if not completely clear after standing at room temperature. This product is stable for 6 months at 4°C as an undiluted liquid. Dilute only prior to immediate use. For extended storage freeze at -20°C or below for 12 months. Avoid cycles of freezing and thawing.
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- 抗原 See all Kallikrein 6 (KLK6) ELISA试剂盒
- Kallikrein 6 (KLK6)
- 别名
- Kallikrein-6 (KLK6 产品)
- 别名
- Bssp ELISA Kit, Klk7 ELISA Kit, PRSS18 ELISA Kit, PRSS9 ELISA Kit, SP59 ELISA Kit, hK6 ELISA Kit, Prss9 ELISA Kit, AI849898 ELISA Kit, BSP ELISA Kit, Klk29 ELISA Kit, MSP ELISA Kit, Prss18 ELISA Kit, neurosin ELISA Kit, kallikrein related peptidase 6 ELISA Kit, kallikrein related-peptidase 6 ELISA Kit, kallikrein-6 ELISA Kit, KLK6 ELISA Kit, Klk6 ELISA Kit, LOC100716801 ELISA Kit
- 基因ID
- 5653
- NCBI登录号
- NP_001012982
- UniProt
- Q92876
- 途径
- Complement System, Regulation of G-Protein Coupled Receptor Protein Signaling
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