CRLF2 ELISA 试剂盒
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- 抗原 See all CRLF2 ELISA试剂盒
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 抗原表位
- AA 20-233
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适用
- 小鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 125 pg/mL - 8000 pg/mL
- 最低检测浓度
- 125 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse CRLF2. 96wells/kit, with removable strips.
- 品牌
- PicoKine™
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: A20-L233
- 灵敏度
- < 10 pg/mL
- 组件
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
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Cytokine Receptor-Like Factor 2 (CRLF2) ELISA Kit
CRLF2 适用: 人 AA 25-231 Colorimetric Sandwich ELISA 156-10.000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Cytokine Receptor-Like Factor 2 (CRLF2) ELISA KitCRLF2 适用: 人 Colorimetric Sandwich ELISA 156-10000 pg/mL Cell Culture Supernatant, Plasma, Serum
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- 实验时间
- 15 min
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all CRLF2 ELISA试剂盒
- CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))
- 别名
- Crlf2 (CRLF2 产品)
- 别名
- CRLF2 ELISA Kit, CRL2 ELISA Kit, CRLF2Y ELISA Kit, TSLPR ELISA Kit, CRLM2 ELISA Kit, Ly114 ELISA Kit, Tpte2 ELISA Kit, Tslpr ELISA Kit, Crl2 ELISA Kit, cytokine receptor like factor 2 ELISA Kit, cytokine receptor-like factor 2 ELISA Kit, CRLF2 ELISA Kit, Crlf2 ELISA Kit
- 背景
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Synonyms: Cytokine receptor-like factor 2, Cytokine receptor-like molecule 2, CRLM-2, Thymic stromal lymphopoietin protein receptor, TSLP receptor, Type I cytokine receptor delta 1, Crlf2, Crlm2, Tpte2, Tslpr
Tissue Specificity: High level of expression in liver, lung and testis. Also expressed in heart, brain, spleen, thymus and bone marrow. Highly expressed in progenitors and myeloid cells. Isoform 2 is expressed in primary hemotopoietic cells.
Background: Cytokine receptor-like factor 2, also known as TSLPR or CRL2, is a protein that in humans is encoded by the CRLF2 gene. It is mapped to Xp22.33. The protein encoded by this gene is a receptor for thymic stromal lymphopoietin(TSLP). Together with the interleukin 7 receptor(IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene. In addition to it, it has been found that rearrangement of CRLF2 and JAK mutation together contribute to leukemogenesis in B-progenitor ALL.
Cellular Localisation: Isoform 1: Cell membrane, Single-pass type I membrane protein. - UniProt
- Q8CII9
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