TIM3 ELISA 试剂盒
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- 抗原 See all TIM3 (TIM 3) ELISA试剂盒
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 抗原表位
- AA 22-202
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 31.2 pg/mL - 2000 pg/mL
- 最低检测浓度
- 31.2 pg/mL
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TIM-3/HAVCR2. 96wells/kit, with removable strips.
- 品牌
- PicoKine™
- 样品类型
- Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: S22-G202
- 灵敏度
- < 10 pg/mL
- 组件
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96-well plate precoated with antibody
lyophilized recombinant standard
biotinylated antibody (dilution 1:100)
Avidin-Biotin-Peroxidase Complex(ABC)(dilution 1:100)
Sample diluent buffer
Antibody diluent buffer
ABC diluent buffer
TMB color developing agent
TMB stop solution
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Hepatitis A Virus Cellular Receptor 2 (TIM 3) ELISA Kit
TIM 3 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Hepatitis A Virus Cellular Receptor 2 (TIM 3) ELISA KitTIM 3 适用: 小鼠 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Lysate, Tissue Homogenate
Hepatitis A Virus Cellular Receptor 2 (TIM 3) ELISA KitTIM 3 适用: 小鼠 AA 20-193 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
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- 实验时间
- 15 min
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all TIM3 (TIM 3) ELISA试剂盒
- TIM3 (TIM 3) (Hepatitis A Virus Cellular Receptor 2 (TIM 3))
- 别名
- HAVCR2 (TIM 3 产品)
- 别名
- HAVCR2 ELISA Kit, MGC140131 ELISA Kit, HAVcr-2 ELISA Kit, KIM-3 ELISA Kit, TIM3 ELISA Kit, TIMD-3 ELISA Kit, TIMD3 ELISA Kit, Tim-3 ELISA Kit, TIM-3 ELISA Kit, Tim3 ELISA Kit, Timd3 ELISA Kit, tim3 ELISA Kit, hepatitis A virus cellular receptor 2 ELISA Kit, HAVCR2 ELISA Kit, Havcr2 ELISA Kit
- 物质类
- Virus
- 背景
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Synonyms: Hepatitis A virus cellular receptor 2, HAVcr-2, T-cell immunoglobulin and mucin domain-containing protein 3, TIMD-3, T-cell immunoglobulin mucin receptor 3, TIM-3, T-cell membrane protein 3, HAVCR2, TIM3, TIMD3
Tissue Specificity: Expressed in T-helper type 1 (Th1) lymphocytes. Expressed on regulatory T (Treg) cells after TCR stimulation. Expressed in dendritic cells and natural killer (NK) cells. Expressed in epithelial tissues. Expression is increased on CD4+ and CD8+ T-cells in chronic hepatitis C virus (HCV) infection. In progressive HIV-1 infection, expression is up- regulated on HIV-1-specific CD8 T-cells.
Background: Hepatitis A virus cellular receptor 2 (HAVCR2), also known as T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), is a protein that in humans is encoded by the HAVCR2 gene. The protein encoded by this gene belongs to the immunoglobulin superfamily, and TIM family of proteins. CD4-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas, Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. This protein is a Th1-specific cell surface protein that regulates macrophage activation, and inhibits Th1-mediated auto- and alloimmune responses, and promotes immunological tolerance.
Cellular Localisation: Membrane, Single-pass type I membrane protein . Cell junction - UniProt
- Q8TDQ0
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Cancer Immune Checkpoints
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