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IL23R ELISA 试剂盒

IL23R 适用: 小鼠 AA 25-373 Colorimetric Sandwich ELISA
产品编号 ABIN5510751
发货至: 中国
  • 抗原 See all IL23R ELISA试剂盒
    IL23R (Interleukin 23 Receptor (IL23R))
    抗原表位
    AA 25-373
    适用
    • 5
    • 2
    • 1
    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse IL-23R
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO, Immunogen sequence: I25-I373
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Expressed by Th1, Th2 and dendritic cells.

    Top Product
    Discover our top product IL23R ELISA Kit
  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • Wang, Deng, Wang, Wu, Gu, Jiang, Li: "MicroRNA-155 in exosomes secreted from helicobacter pylori infection macrophages immunomodulates inflammatory response." in: American journal of translational research, Vol. 8, Issue 9, pp. 3700-3709, (2016) (PubMed).

  • 抗原 See all IL23R ELISA试剂盒
    IL23R (Interleukin 23 Receptor (IL23R))
    别名
    Il23r (IL23R 产品)
    别名
    IL-23R ELISA Kit, IL23R ELISA Kit, il-23r ELISA Kit, interleukin 23 receptor ELISA Kit, IL23R ELISA Kit, il23r ELISA Kit, Il23r ELISA Kit
    背景

    Protein Function: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis (By similarity). .

    Background: Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.

    Synonyms: Interleukin-23 receptor, IL-23 receptor, IL-23R, Il23r,

    Full Gene Name: interleukin 23 receptor

    Cellular Localisation: Cell membrane, Single-pass type I membrane protein.
    UniProt
    Q8K4B4
    途径
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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