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- 抗原 See all IL23R ELISA试剂盒
- IL23R (Interleukin 23 Receptor (IL23R))
- 抗原表位
- AA 25-354
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human IL-23R
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: I25-I354
- 交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells.
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- Discover our top product IL23R ELISA Kit
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Interleukin 23 Receptor (IL23R) ELISA Kit
IL23R 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate
Interleukin 23 Receptor (IL23R) ELISA KitIL23R 适用: 大鼠 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Lysate, Tissue Homogenate
Interleukin 23 Receptor (IL23R) ELISA KitIL23R 适用: 小鼠 AA 25-373 Colorimetric Sandwich ELISA
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all IL23R ELISA试剂盒
- IL23R (Interleukin 23 Receptor (IL23R))
- 别名
- IL23R (IL23R 产品)
- 别名
- IL-23R ELISA Kit, IL23R ELISA Kit, il-23r ELISA Kit, interleukin 23 receptor ELISA Kit, IL23R ELISA Kit, il23r ELISA Kit, Il23r ELISA Kit
- 背景
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Protein Function: Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
Background: Interleukin-23 subunit alpha is a protein that in humans is encoded by the IL23A gene. The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
Synonyms: Interleukin-23 receptor, IL-23 receptor, IL-23R, IL23R,
Full Gene Name: interleukin 23 receptor
Cellular Localisation: Cell membrane - UniProt
- Q5VWK5
- 途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
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