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- 抗原 See all Angiopoietin 2 (ANGPT2) ELISA试剂盒
- Angiopoietin 2 (ANGPT2)
- 抗原表位
- AA 19-496
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适用
- 大鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Rat Angiopoietin-2
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: Y19-F496 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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- Discover our best selling ANGPT2 ELISA Kit
- Top Product
- Discover our top product ANGPT2 ELISA Kit
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 924-932, (2018) (PubMed).
: "Autonomic remodeling may be responsible for decreased incidence of aortic dissection in STZ-induced diabetic rats via down-regulation of matrix metalloprotease 2." in: BMC cardiovascular disorders, Vol. 16, Issue 1, pp. 200, (2017) (PubMed).
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Vaccarin alleviates hypertension and nephropathy in renovascular hypertensive rats." in: Experimental and therapeutic medicine, Vol. 15, Issue 1, pp. 924-932, (2018) (PubMed).
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- 抗原 See all Angiopoietin 2 (ANGPT2) ELISA试剂盒
- Angiopoietin 2 (ANGPT2)
- 别名
- Angpt2 (ANGPT2 产品)
- 别名
- AGPT2 ELISA Kit, ANG2 ELISA Kit, Agpt2 ELISA Kit, Ang-2 ELISA Kit, Ang2 ELISA Kit, ang2 ELISA Kit, angpt2 ELISA Kit, ANGIOPOIETIN-2 ELISA Kit, ANG-2 ELISA Kit, ANGPT2 ELISA Kit, Angrp ELISA Kit, Rnase5b ELISA Kit, ANG3 ELISA Kit, C11orf2 ELISA Kit, C11orf3 ELISA Kit, FFR ELISA Kit, angiopoietin 2 ELISA Kit, angiopoietin 2b ELISA Kit, angiogenin, ribonuclease A family, member 2 ELISA Kit, VPS51, GARP complex subunit ELISA Kit, ANGPT2 ELISA Kit, Angpt2 ELISA Kit, angpt2b ELISA Kit, Ang2 ELISA Kit, VPS51 ELISA Kit
- 背景
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Protein Function: Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal (By similarity). .
Background: Angiopoietin-2 is a protein that in humans is encoded by the ANGPT2 gene. Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. ANGPT2 is a naturally occurring antagonist of angiopoietin-1 that competes for binding to the TIE2 receptor and blocks ANGPT1-induced TIE2 autophosphorylation during vasculogenesis. Its expression occurs at sites of vascular remodelling: dorsal aorta and major aortic branches, ovary, placenta and uterus.
Synonyms: Angiopoietin-2,ANG-2,Angpt2,Agpt2,
Full Gene Name: Angiopoietin-2
Cellular Localisation: Secreted. - UniProt
- O35462
- 途径
- RTK signaling
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