GDF2 ELISA 试剂盒
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- 抗原 See all GDF2 ELISA试剂盒
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- 抗原表位
- AA 320-429
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human BMP-9
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: CHO, Immunogen sequence: S320-R429
- 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all GDF2 ELISA试剂盒
- GDF2 (Growth Differentiation Factor 2 (GDF2))
- 别名
- GDF2 (GDF2 产品)
- 别名
- bmp9 ELISA Kit, BMP-9 ELISA Kit, BMP9 ELISA Kit, Bmp9 ELISA Kit, DSL1 ELISA Kit, growth differentiation factor 2 ELISA Kit, gdf2 ELISA Kit, GDF2 ELISA Kit, Gdf2 ELISA Kit
- 背景
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Protein Function: Potent circulating inhibitor of angiogenesis. Could be involved in bone formation. Signals through the type I activin receptor ACVRL1 but not other Alks. Signaling through SMAD1 in endothelial cells requires TGF-beta coreceptor endoglin/ENG.
Background: Growth differentiation factor 2 (GDF2) also known as bone morphogenetic protein (BMP)-9 is a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Homozygous null mice exhibit malformations of the vasculature and skeleton.
Synonyms: Growth/differentiation factor 2, GDF-2, Bone morphogenetic protein 9, BMP-9, GDF2, BMP9,
Full Gene Name: growth differentiation factor 2
Cellular Localisation: Secreted - UniProt
- Q9UK05
- 途径
- Transition Metal Ion Homeostasis
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