PVRL4 ELISA 试剂盒
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- 抗原 See all PVRL4 ELISA试剂盒
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- 抗原表位
- AA 32-349
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Nectin-4
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: G32-S349 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Predominantly expressed in placenta. Not detected in normal breast epithelium but expressed in breast carcinoma. .
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all PVRL4 ELISA试剂盒
- PVRL4 (Poliovirus Receptor-Related 4 (PVRL4))
- 别名
- NECTIN4 (PVRL4 产品)
- 别名
- PVRL4 ELISA Kit, si:ch211-155e24.1 ELISA Kit, 1200017F15Rik ELISA Kit, Prr4 ELISA Kit, RGD1559826 ELISA Kit, EDSS1 ELISA Kit, LNIR ELISA Kit, PRR4 ELISA Kit, nectin-4 ELISA Kit, nectin cell adhesion molecule 4 ELISA Kit, NECTIN4 ELISA Kit, nectin4 ELISA Kit, Nectin4 ELISA Kit
- 背景
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Protein Function: Seems to be involved in cell adhesion through trans- homophilic and -heterophilic interactions, the latter including specifically interactions with NECTIN1. Does not act as receptor for alpha-herpesvirus entry into cells.
Background: Nectin-4, also known as PVRL4, is an adhesion receptor of the immunoglobulin superfamily and functions in cell-cell adhesion. This gene is mapped to chromosome 1q23.3. The encoded protein contains two immunoglobulin-like (Ig-like) C2-type domains and one Ig-like V-type domain. It is involved in cell adhesion through trans-homophilic and -heterophilic interactions. It is a single-pass type I membrane protein. The soluble form is produced by proteolytic cleavage at the cell surface by the metalloproteinase ADAM17/TACE. The secreted form is found in both breast tumor cell lines and breast tumor patients. Mutations in this gene are the cause of ectodermal dysplasia-syndactyly syndrome type 1, an autosomal recessive disorder. Alternatively spliced transcript variants have been found but the full-length nature of the variant has not been determined.
Synonyms: Nectin-4,Ig superfamily receptor LNIR,Nectin cell adhesion molecule 4 ,Poliovirus receptor-related protein 4,Processed poliovirus receptor-related protein 4,NECTIN4 ,LNIR, PRR4, PVRL4,
Full Gene Name: Nectin-4
Cellular Localisation: Cell membrane, Single-pass type I membrane protein . Cell junction, adherens junction . Colocalizes with MLLT4 at cadherin-based adherens junctions (PubMed:11544254). - UniProt
- Q96NY8
- 途径
- Cell-Cell Junction Organization
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