CPB2 ELISA 试剂盒
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- 抗原 See all CPB2 ELISA试剂盒
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
- 抗原表位
- AA 1-423
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TAFI/CPB2
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: M1-V423 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Plasma, synthesized in the liver.
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all CPB2 ELISA试剂盒
- CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
- 别名
- CPB2 (CPB2 产品)
- 别名
- CPU ELISA Kit, PCPB ELISA Kit, TAFI ELISA Kit, 1110032P04Rik ELISA Kit, 4930405E17Rik ELISA Kit, AI255929 ELISA Kit, CPR ELISA Kit, Cpu ELISA Kit, pCPB ELISA Kit, zgc:112493 ELISA Kit, carboxypeptidase B2 ELISA Kit, carboxypeptidase B2 (plasma) ELISA Kit, CPB2 ELISA Kit, Cpb2 ELISA Kit, cpb2 ELISA Kit
- 背景
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Protein Function: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. .
Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.
Synonyms: Carboxypeptidase B2,3.4.17.20 ,Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI,CPB2,
Full Gene Name: Carboxypeptidase B2
Cellular Localisation: Secreted. - UniProt
- Q96IY4
- 途径
- Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
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