电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CPB2 ELISA 试剂盒

CPB2 适用: 人 AA 1-423 Colorimetric Sandwich ELISA
产品编号 ABIN5510667
发货至: 中国
  • 抗原 See all CPB2 ELISA试剂盒
    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
    抗原表位
    AA 1-423
    适用
    • 9
    • 5
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human TAFI/CPB2
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO
    Immunogen sequence: M1-V423
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Plasma, synthesized in the liver.

    Featured
    Discover our best selling CPB2 ELISA Kit
    Top Product
    Discover our top product CPB2 ELISA Kit
  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all CPB2 ELISA试剂盒
    CPB2 (Carboxypeptidase B2 (Plasma) (CPB2))
    别名
    CPB2 (CPB2 产品)
    背景

    Protein Function: Cleaves C-terminal arginine or lysine residues from biologically active peptides such as kinins or anaphylatoxins in the circulation thereby regulating their activities. Down- regulates fibrinolysis by removing C-terminal lysine residues from fibrin that has already been partially degraded by plasmin. .

    Background: Carboxypeptidase B2 (CPB2), also known as carboxypeptidase U (CPU), plasma carboxypeptidase B (pCPB) or thrombin-activatable fibrinolysis inhibitor (TAFI), is an enzyme that, in humans, is encoded by the gene CPB2. CPB2 is synthesized by the liver and circulates in the plasma as a plasminogen-bound zymogen. When it is activated by proteolysis at residue Arg92 by the thrombin/thrombomodulin complex, CPB2 exhibits carboxypeptidase activity. Activated CPB2 reduces fibrinolysis by removing the fibrin C-terminal residues that are important for the binding and activation of plasminogen.

    Synonyms: Carboxypeptidase B2,3.4.17.20 ,Carboxypeptidase U,CPU,Plasma carboxypeptidase B,pCPB,Thrombin-activable fibrinolysis inhibitor,TAFI,CPB2,

    Full Gene Name: Carboxypeptidase B2

    Cellular Localisation: Secreted.
    UniProt
    Q96IY4
    途径
    Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis
You are here:
客服