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- 抗原 See all WFDC2 ELISA试剂盒
- WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
- 抗原表位
- AA 31-124
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human HE4
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: E.coli
Immunogen sequence: E31-F124 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. Highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. .
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." in: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).
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Value of HE4 Combined with Cancer Antigen 125 in the Diagnosis of Endometrial Cancer." in: Pakistan journal of medical sciences, Vol. 33, Issue 4, pp. 1013-1017, (2017) (PubMed).
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- 抗原 See all WFDC2 ELISA试剂盒
- WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))
- 别名
- WFDC2 (WFDC2 产品)
- 别名
- WFDC3 ELISA Kit, WFDC2 ELISA Kit, si:ch211-153a8.3 ELISA Kit, EDDM4 ELISA Kit, HE4 ELISA Kit, WAP5 ELISA Kit, dJ461P17.6 ELISA Kit, 1600023A02Rik ELISA Kit, re4 ELISA Kit, CE4 ELISA Kit, BE-20 ELISA Kit, WAP four-disulfide core domain 2 ELISA Kit, WFDC2 ELISA Kit, wfdc2 ELISA Kit, Wfdc2 ELISA Kit
- 背景
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Protein Function: Broad range protease inhibitor. .
Background: WAP four-disulfide core domain protein 2, also known as Human Epididymis Protein 4 (HE4), is a protein that in humans is encoded by the WFDC2 gene. This gene encodes a protein that is a member of the WFDC domain family. The WFDC domain, or WAP Signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor in many family members. This gene is expressed in pulmonary epithelial cells, and was also found to be expressed in some ovarian cancers. The encoded protein is a small secretory protein, which may be involved in sperm maturation.
Synonyms: WAP four-disulfide core domain protein 2,Epididymal secretory protein E4,Major epididymis-specific protein E4,Putative protease inhibitor WAP5,WFDC2,HE4, WAP5,
Full Gene Name: WAP four-disulfide core domain protein 2
Cellular Localisation: Secreted. - UniProt
- Q14508
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