PDCD1LG2 ELISA 试剂盒
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- 抗原 See all PDCD1LG2 ELISA试剂盒
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 抗原表位
- AA 20-220
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human PD-L2/B7-DC
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: L20-T220
- 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Highly expressed in heart, placenta, pancreas, lung and liver and weakly expressed in spleen, lymph nodes and thymus.
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all PDCD1LG2 ELISA试剂盒
- PDCD1LG2 (Programmed Cell Death 1 Ligand 2 (PDCD1LG2))
- 别名
- PDCD1LG2 (PDCD1LG2 产品)
- 别名
- PDL2 ELISA Kit, B7DC ELISA Kit, Btdc ELISA Kit, CD273 ELISA Kit, PD-L2 ELISA Kit, PDCD1L2 ELISA Kit, bA574F11.2 ELISA Kit, B7-DC ELISA Kit, F730015O22Rik ELISA Kit, programmed cell death 1 ligand 2 ELISA Kit, PDCD1LG2 ELISA Kit, Pdcd1lg2 ELISA Kit
- 背景
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Protein Function: Involved in the costimulatory signal, essential for T- cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production (By similarity). .
Background: Programmed cell death 1 ligand 2 (also known as PD-L2, B7-DC) is a protein that in humans is encoded by the PDCD1LG2 gene. It is mapped to chromosome 9p24.2. PD-L2 is one of two ligands for programmed death-1 (PD-1), a member of the CD28 family of immuno-receptors. Northern blot analysis detect wide expression of PDL2, with highest levels in placenta, heart, pancreas, lung, and liver, and lower levels in spleen, lymph nodes, and thymus. PDL2 negatively regulates T cells and plays an essential role in immune tolerance.
Synonyms: Programmed cell death 1 ligand 2, PD-1 ligand 2, PD-L2, PDCD1 ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, B7-DC, CD273, PDCD1LG2, B7DC, CD273, PDCD1L2, PDL2,
Full Gene Name: programmed cell death 1 ligand 2
Cellular Localisation: Isoform 3: Secreted - UniProt
- Q9BQ51
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