Epiregulin ELISA 试剂盒
-
- 抗原 See all Epiregulin (EREG) ELISA试剂盒
- Epiregulin (EREG)
- 抗原表位
- AA 60-108
-
适用
- 猴
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate Epiregulin
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- E.coli, V60-L108
- 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
-
Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. .
- Featured
- Discover our best selling EREG ELISA Kit
- Top Product
- Discover our top product EREG ELISA Kit
-
-
- 板类型
- Pre-coated
- 限制
- 仅限研究用
-
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
-
- 抗原 See all Epiregulin (EREG) ELISA试剂盒
- Epiregulin (EREG)
- 别名
- EREG (EREG 产品)
- 别名
- EREG ELISA Kit, ER ELISA Kit, EPR ELISA Kit, proepiregulin ELISA Kit, epiregulin ELISA Kit, EREG ELISA Kit, ereg ELISA Kit, Ereg ELISA Kit
- 背景
-
Protein Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .
Background: Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.
Synonyms: Proepiregulin,Epiregulin,EPR,EREG,
Full Gene Name: Proepiregulin
Cellular Localisation: Epiregulin: Secreted, extracellular space. - UniProt
- O14944
- 途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
-