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Epiregulin ELISA 试剂盒

EREG 适用: 猴 AA 60-108 Colorimetric Sandwich ELISA
产品编号 ABIN5510631
发货至: 中国
  • 抗原 See all Epiregulin (EREG) ELISA试剂盒
    Epiregulin (EREG)
    抗原表位
    AA 60-108
    适用
    • 9
    • 8
    • 4
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate Epiregulin
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    E.coli, V60-L108
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. .

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all Epiregulin (EREG) ELISA试剂盒
    Epiregulin (EREG)
    别名
    EREG (EREG 产品)
    背景

    Protein Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .

    Background: Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.

    Synonyms: Proepiregulin,Epiregulin,EPR,EREG,

    Full Gene Name: Proepiregulin

    Cellular Localisation: Epiregulin: Secreted, extracellular space.
    UniProt
    O14944
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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