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Epiregulin ELISA 试剂盒

EREG 适用: 猴 AA 60-108 Colorimetric Sandwich ELISA
产品编号 ABIN5510631
发货至: 中国
  • 抗原 See all Epiregulin (EREG) ELISA试剂盒
    Epiregulin (EREG)
    抗原表位
    AA 60-108
    适用
    • 7
    • 7
    • 3
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of monkey primate Epiregulin
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    E.coli, V60-L108
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: In normal adults, expressed predominantly in the placenta and peripheral blood leukocytes. High levels were detected in carcinomas of the bladder, lung, kidney and colon. .

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all Epiregulin (EREG) ELISA试剂盒
    Epiregulin (EREG)
    别名
    EREG (EREG 产品)
    别名
    EREG ELISA Kit, ER ELISA Kit, EPR ELISA Kit, proepiregulin ELISA Kit, epiregulin ELISA Kit, EREG ELISA Kit, ereg ELISA Kit, Ereg ELISA Kit
    背景

    Protein Function: Ligand of the EGF receptor/EGFR and ERBB4. Stimulates EGFR and ERBB4 tyrosine phosphorylation (PubMed:9419975). Contributes to inflammation, wound healing, tissue repair, and oocyte maturation by regulating angiogenesis and vascular remodeling and by stimulating cell proliferation (PubMed:24631357). .

    Background: Epiregulin (EPR) is a protein that in humans is encoded by the EREG gene. It is a member of the epidermal growth factor family. Epiregulin can function as a ligand of epidermal growth factor receptor (EGFR), as well as a ligand of most members of the ERBB (v-erb-b2 oncogene homolog) family of tyrosine-kinase receptors. The secondary structure at the C-terminus epiregulin is different from other epidermal growth factor family ligands because of the lack of hydrogen bonds. The structural difference at the C-terminus may provide an explanation for the reduced binding affinity of epiregulin to the ERBB receptors.

    Synonyms: Proepiregulin,Epiregulin,EPR,EREG,

    Full Gene Name: Proepiregulin

    Cellular Localisation: Epiregulin: Secreted, extracellular space.
    UniProt
    O14944
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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