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- 抗原 See all GZMB ELISA试剂盒
- GZMB (Granzyme B (GZMB))
- 抗原表位
- AA 21-247
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适用
- 小鼠
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Mouse Granzyme B
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: I21-S247
- 交叉反应 （详细）
- There is no detectable cross-reactivity with other relevant proteins.
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- Discover our top product GZMB ELISA Kit
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Granzyme B (GZMB) ELISA Kit
GZMB 适用: 人 Colorimetric Sandwich ELISA 0.15 ng/mL - 10 ng/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granzyme B (GZMB) ELISA KitGZMB 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Granzyme B (GZMB) ELISA KitGZMB 适用: 大鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Granzyme B (GZMB) ELISA KitGZMB 适用: 猴 Colorimetric Sandwich ELISA 15.63 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma, Serum
Granzyme B (GZMB) ELISA KitGZMB 适用: 人 AA 21-247 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Granzyme B (GZMB) ELISA KitGZMB 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all GZMB ELISA试剂盒
- GZMB (Granzyme B (GZMB))
- 别名
- Gzmb (GZMB 产品)
- 别名
- CCPI ELISA Kit, CGL-1 ELISA Kit, CGL1 ELISA Kit, CSP-B ELISA Kit, CSPB ELISA Kit, CTLA1 ELISA Kit, CTSGL1 ELISA Kit, HLP ELISA Kit, SECT ELISA Kit, granzyme B ELISA Kit, GZMB ELISA Kit
- 背景
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Protein Function: This enzyme is necessary for target cell lysis in cell- mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis (By similarity). .
Background: Granzyme B is a serine protease that in humans is encoded by the GZMB gene. Granzyme B is expressed by cytotoxic T lymphocytes (CTL) and natural killer (NK) cells. CTL and NK cells share the remarkable ability to recognize specific infected target cells. They are thought to protect their host by inducing apoptosis of cells that bear on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein encoded by this gene is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
Synonyms: Granzyme B(G,H),3.4.21.79,CTLA-1,Cytotoxic cell protease 1,CCP1,Fragmentin-2,Gzmb,Ctla-1, Ctla1,
Full Gene Name: Granzyme B(G,H)
Cellular Localisation: Cytoplasmic granule. Cytoplasmic granules of cytolytic T-lymphocytes and natural killer cells. - UniProt
- P04187
- 途径
- Apoptosis, Caspase Cascade in Apoptosis
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