Sclerostin ELISA 试剂盒
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- 抗原 See all Sclerostin (SOST) ELISA试剂盒
- Sclerostin (SOST)
- 抗原表位
- AA 24-213
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Human Sclerostin/SOST
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
- Expression system for standard: NSO, Immunogen sequence: Q24-Y213
- 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Tissue Specificity: Widely expressed at low levels with highest levels in bone, cartilage, kidney, liver, bone marrow and primary osteoblasts differentiated for 21 days. Detected in the subendothelial layer of the aortic intima (at protein level). .
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- Discover our top product SOST ELISA Kit
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all Sclerostin (SOST) ELISA试剂盒
- Sclerostin (SOST)
- 别名
- SOST (SOST 产品)
- 别名
- LOC100313724 ELISA Kit, CDD ELISA Kit, VBCH ELISA Kit, 5430411E23Rik ELISA Kit, sclerostin ELISA Kit, LOC100313724 ELISA Kit, SOST ELISA Kit, Sost ELISA Kit
- 背景
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Protein Function: Negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation. .
Background: Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Additionally, Sclerostin is produced by the osteocyte and has anti-anabolic effects on bone formation. The SOST gene maps to chromosome 17q12-q21.
Synonyms: Sclerostin,SOST,UNQ2976/PRO7455/PRO7476,
Full Gene Name: Sclerostin
Cellular Localisation: Secreted, extracellular space, extracellular matrix. - UniProt
- Q9BQB4
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