IL29 ELISA 试剂盒
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- 抗原 See all IL29 ELISA试剂盒
- IL29 (Interleukin 29 (IL29))
- 抗原表位
- AA 20-200
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适用
- 犬
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Dog Caninea IL-29
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: G20-T200 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Sequence similarities: Belongs to the lambda interferon family.
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all IL29 ELISA试剂盒
- IL29 (Interleukin 29 (IL29))
- 别名
- IFNL1 (IL29 产品)
- 别名
- IL-29 ELISA Kit, IL29 ELISA Kit, interferon lambda 1 ELISA Kit, interferon lambda-1 ELISA Kit, interleukin 29 (interferon, lambda 1) ELISA Kit, IFNL1 ELISA Kit, LOC612539 ELISA Kit, IL29 ELISA Kit
- 背景
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Protein Function: Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN- stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type- selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.
Background: Interferon lambda-1, also called Interleukin-29(IL-29) is a protein that in Dog Canineas is encoded by the IL29 gene. IL-29 is a member of the helical cytokine family and is a type III interferon. This gene is mapped to 19q13.2. It is a cytokine with immunomodulatory activity. This gene may play a role in antiviral immunity. It can up-regulates MHC class I antigen expression. It is the ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-29 plays an important role in host defenses against microbes and its gene is highly upregulated in cells infected with viruses.
Synonyms: Interferon lambda-1,IFN-lambda-1,Cytokine Zcyto21,Interleukin-29,IL-29,IFNL1,IL29, ZCYTO21,
Full Gene Name: Interferon lambda-1
Cellular Localisation: Secreted. - UniProt
- Q8IU54
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