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N-Cadherin ELISA 试剂盒

CDH2 适用: 兔 AA 160-724 Colorimetric Sandwich ELISA
产品编号 ABIN5510582
发货至: 中国
  • 抗原 See all N-Cadherin (CDH2) ELISA试剂盒
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    抗原表位
    AA 160-724
    适用
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of rabbit Cadherin-2/N-Cadherin
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: NSO
    Immunogen sequence: D160-A724
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all N-Cadherin (CDH2) ELISA试剂盒
    N-Cadherin (CDH2) (Cadherin 2 (CDH2))
    别名
    CDH2 (CDH2 产品)
    别名
    CD325 ELISA Kit, CDHN ELISA Kit, CDw325 ELISA Kit, NCAD ELISA Kit, N-cadherin ELISA Kit, cadherin-2 ELISA Kit, cdhn ELISA Kit, ncad ELISA Kit, cdw325 ELISA Kit, CDH2 ELISA Kit, Cadherin-2 ELISA Kit, Ncad ELISA Kit, glo ELISA Kit, lyr ELISA Kit, pac ELISA Kit, wu:fb47h04 ELISA Kit, cadherin 2 ELISA Kit, cadherin 2 S homeolog ELISA Kit, cadherin 2, type 1, N-cadherin (neuronal) ELISA Kit, CDH2 ELISA Kit, cdh2.S ELISA Kit, cdh2 ELISA Kit, Cdh2 ELISA Kit
    背景

    Protein Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). .

    Background: Cadherin-2(CDH2), also known as neural cadherin(NCAD), is a protein that in humans is encoded by the CDH2 gene. It is a classical cadherin from the cadherin superfamily. This gene is mapped to 18q12.1. Cadherin-2 is expressed in the brain, skeletal and cardiac muscle. Cadherin-2 is commonly found in cancer cells and provides a mechanism for transendothelial migration. It is a calcium dependent cell-cell adhesion glycoprotein comprising five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.

    Synonyms: Cadherin-2,CDw325,Neural cadherin,N-cadherin,CD325,CDH2,CDHN, NCAD,

    Full Gene Name: Cadherin-2

    Cellular Localisation: Cell membrane, Single-pass type I membrane protein.
    UniProt
    P19022
    途径
    Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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