N-Cadherin ELISA 试剂盒
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- 抗原 See all N-Cadherin (CDH2) ELISA试剂盒
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- 抗原表位
- AA 160-724
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适用
- 犬
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Dog Caninea Cadherin-2/N-Cadherin
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: D160-A724 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
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- Discover our top product CDH2 ELISA Kit
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4 °C for 6 months, at -20 °C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
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- 抗原 See all N-Cadherin (CDH2) ELISA试剂盒
- N-Cadherin (CDH2) (Cadherin 2 (CDH2))
- 别名
- CDH2 (CDH2 产品)
- 别名
- CD325 ELISA Kit, CDHN ELISA Kit, CDw325 ELISA Kit, NCAD ELISA Kit, N-cadherin ELISA Kit, cadherin-2 ELISA Kit, cdhn ELISA Kit, ncad ELISA Kit, cdw325 ELISA Kit, CDH2 ELISA Kit, Cadherin-2 ELISA Kit, Ncad ELISA Kit, glo ELISA Kit, lyr ELISA Kit, pac ELISA Kit, wu:fb47h04 ELISA Kit, cadherin 2 ELISA Kit, cadherin 2 S homeolog ELISA Kit, cadherin 2, type 1, N-cadherin (neuronal) ELISA Kit, CDH2 ELISA Kit, cdh2.S ELISA Kit, cdh2 ELISA Kit, Cdh2 ELISA Kit
- 背景
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Protein Function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. Acts as a regulator of neural stem cells quiescence by mediating anchorage of neural stem cells to ependymocytes in the adult subependymal zone: upon cleavage by MMP24, CDH2-mediated anchorage is affected, leading to modulate neural stem cell quiescence. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density (By similarity). .
Background: Cadherin-2(CDH2), also known as neural cadherin(NCAD), is a protein that in Dog Canineas is encoded by the CDH2 gene. It is a classical cadherin from the cadherin superfamily. This gene is mapped to 18q12.1. Cadherin-2 is expressed in the brain, skeletal and cardiac muscle. Cadherin-2 is commonly found in cancer cells and provides a mechanism for transendothelial migration. It is a calcium dependent cell-cell adhesion glycoprotein comprising five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product.
Synonyms: Cadherin-2,CDw325,Neural cadherin,N-cadherin,CD325,CDH2,CDHN, NCAD,
Full Gene Name: Cadherin-2
Cellular Localisation: Cell membrane, Single-pass type I membrane protein. - UniProt
- P19022
- 途径
- Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Synaptic Membrane
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