TIMP3 ELISA 试剂盒
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- 抗原 See all TIMP3 ELISA试剂盒
- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
- 抗原表位
- AA 24-211
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适用
- Pig
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 应用范围
- ELISA
- 原理
- Sandwich High Sensitivity ELISA kit for Quantitative Detection of Pig porcine TIMP-3
- 品牌
- PicoKine™
- Analytical Method
- Quantitative
- 特异性
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Expression system for standard: NSO
Immunogen sequence: C24-P211 - 交叉反应 (详细)
- There is no detectable cross-reactivity with other relevant proteins.
- 产品特性
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Sequence similarities: Belongs to the protease inhibitor I35 (TIMP) family.
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- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
- 有效期
- 12 months
-
- 抗原 See all TIMP3 ELISA试剂盒
- TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
- 别名
- TIMP3 (TIMP3 产品)
- 别名
- TIMP-3 ELISA Kit, TIMP3 ELISA Kit, timp3 ELISA Kit, HSMRK222 ELISA Kit, K222 ELISA Kit, K222TA2 ELISA Kit, SFD ELISA Kit, IMP-3 ELISA Kit, timp3-A ELISA Kit, Timp-3 ELISA Kit, metalloproteinase inhibitor 3 ELISA Kit, TIMP metallopeptidase inhibitor 3 ELISA Kit, Metalloproteinase inhibitor 3 ELISA Kit, TIMP metallopeptidase inhibitor 3 L homeolog ELISA Kit, tissue inhibitor of metalloproteinase 3 ELISA Kit, CpipJ_CPIJ003282 ELISA Kit, TIMP3 ELISA Kit, timp3 ELISA Kit, Timp3 ELISA Kit, timp3.L ELISA Kit
- 背景
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Protein Function: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Background: The tissue inhibitors of metalloproteinases(TIMPs) are natural inhibitors of the matrix metalloproteinases, a group of zinc-binding endopeptidases involved in the degradation of the extracellular matrix. The TIMP3 gene is expressed in many tissues, with highest expression in the placenta. TIMP3 encodes a potent angiogenesis inhibitor and is mutated in Sorsby fundus dystrophy, a macular degenerative disease with submacular choroidal neovascularization. TIMP3 gene is mapped to 22q12.1-q13.2. Mutations in TIMP3 cause the autosomal dominant disorder Sorsby's fundus dystrophy(SFD).
Synonyms: Metalloproteinase inhibitor 3,Protein MIG-5,Tissue inhibitor of metalloproteinases 3,TIMP-3,TIMP3,
Full Gene Name: Metalloproteinase inhibitor 3
Cellular Localisation: Secreted, extracellular space, extracellular matrix. - UniProt
- P35625
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