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FGF1 ELISA 试剂盒

FGF1 适用: 马 AA 2-155 Colorimetric Sandwich ELISA
产品编号 ABIN5510539
发货至: 中国
  • 抗原 See all FGF1 ELISA试剂盒
    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
    抗原表位
    AA 2-155
    适用
    • 11
    • 8
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    • 5
    • 4
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    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    应用范围
    ELISA
    原理
    Sandwich High Sensitivity ELISA kit for Quantitative Detection of horse equine FGF1
    品牌
    PicoKine™
    Analytical Method
    Quantitative
    特异性
    Expression system for standard: E.coli
    Immunogen sequence: A2-D155
    交叉反应 (详细)
    There is no detectable cross-reactivity with other relevant proteins.
    产品特性

    Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .

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  • 板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C,-20 °C
    储存方法
    Store at 4°C for 6 months, at -20°C for 12 months. Avoid multiple freeze-thaw cycles(Shipped with wet ice.)
    有效期
    12 months
  • 抗原 See all FGF1 ELISA试剂盒
    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
    别名
    FGF1 (FGF1 产品)
    别名
    AFGF ELISA Kit, ECGF ELISA Kit, ECGF-beta ELISA Kit, ECGFA ELISA Kit, ECGFB ELISA Kit, FGF-1 ELISA Kit, FGF-alpha ELISA Kit, FGFA ELISA Kit, GLIO703 ELISA Kit, HBGF-1 ELISA Kit, HBGF1 ELISA Kit, Fgf1 ELISA Kit, FGF1 ELISA Kit, aFGF ELISA Kit, ecgf ELISA Kit, fgfa ELISA Kit, ecgfa ELISA Kit, ecgfb ELISA Kit, fgf-1 ELISA Kit, hbgf1 ELISA Kit, glio703 ELISA Kit, ecgf-beta ELISA Kit, fgf-alpha ELISA Kit, Dffrx ELISA Kit, Fam ELISA Kit, Fgf-1 ELISA Kit, Fgfa ELISA Kit, zgc:136885 ELISA Kit, LOC100221393 ELISA Kit, fgf1 ELISA Kit, zgc:73249 ELISA Kit, fibroblast growth factor 1 ELISA Kit, fibroblast growth factor 1 L homeolog ELISA Kit, fibroblast growth factor 1b ELISA Kit, fibroblast growth factor 1a ELISA Kit, FGF1 ELISA Kit, fgf1.L ELISA Kit, fgf1 ELISA Kit, Fgf1 ELISA Kit, fgf1b ELISA Kit, LOC100221393 ELISA Kit, fgf1a ELISA Kit
    背景

    Protein Function: Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. .

    Background: Heparin-binding growth factor 1 is a protein that in humans is encoded by the FGF1 gene. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. The FGF1 gene was mapped to chromosome 5q31.3-q33.2 by in situ hybridization.

    Synonyms: Fibroblast growth factor 1,FGF-1,Acidic fibroblast growth factor,aFGF,Endothelial cell growth factor,ECGF,Heparin-binding growth factor 1,HBGF-1,FGF1,FGFA,

    Full Gene Name: Fibroblast growth factor 1

    Cellular Localisation: Secreted. Cytoplasm. Cytoplasm, cell cortex. Cytoplasm, cytosol. Nucleus. Lacks a cleavable signal sequence. Within the cytoplasm, it is transported to the cell membrane and then secreted by a non-classical pathway that requires Cu(2+) ions and S100A13. Secreted in a complex with SYT1 (By similarity). Binding of exogenous FGF1 to FGFR facilitates endocytosis followed by translocation of FGF1 across endosomal membrane into the cytosol. Nuclear import from the cytosol requires the classical nuclear import machinery, involving proteins KPNA1 and KPNB1, as well as LRRC59..
    UniProt
    P05230
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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