电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

IL-5 ELISA 试剂盒

IL5 适用: 小鼠 Colorimetric Sandwich ELISA 0.02-1.0 ng/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (citrate), Plasma (heparin), Serum
产品编号 ABIN4986960
发货至: 中国
  • 抗原 See all IL-5 (IL5) ELISA试剂盒
    IL-5 (IL5) (Interleukin 5 (IL5))
    适用
    • 16
    • 11
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    小鼠
    检测方法
    Colorimetric
    实验类型
    Sandwich ELISA
    检测范围
    0.02-1.0 ng/mL
    最低检测浓度
    0.02 ng/mL
    应用范围
    ELISA
    样品类型
    Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
    Analytical Method
    Quantitative
    特异性
    Natural and recombinant Mouse IL-5 Ligand
    灵敏度
    7 pg/mL
    试剂未包括
    • Microplate reader.
    • Pipettes and pipette tips.
    • EP tube Deionized or distilled water.
    Featured
    Discover our best selling IL5 ELISA Kit
    Top Product
    Discover our top product IL5 ELISA Kit
  • 应用备注
    Detection Wavelength: 450 nm
    样本量
    20 μL
    实验时间
    3 h
    板类型
    Pre-coated
    限制
    仅限研究用
  • 储存条件
    4 °C
  • 抗原 See all IL-5 (IL5) ELISA试剂盒
    IL-5 (IL5) (Interleukin 5 (IL5))
    别名
    IL-5 (IL5 产品)
    别名
    EDF ELISA Kit, IL-5 ELISA Kit, TRF ELISA Kit, Il-5 ELISA Kit, IL5 ELISA Kit, interleukin 5 ELISA Kit, IL5 ELISA Kit, Il5 ELISA Kit
    背景
    Mouse interleukin 5 (mIL-5), also known as T-cell replacing factor, B-cell growth factor II, eosinophil differentiation factor and eosinophil colony stimulating factor, is a pleiotropic cytokine produced primarily by T cells (1-4). It supports the proliferation and differentiation of mouse, but not human, B cells, and enhances IgM, IgG1, IgA, and IgE secretion. IL-5 chemoattracts and enhances the survival and the effector functions of mature eosinophils and synergizes with various colony stimulating factors to increase eosinophil progenitor production and eosinophil expansion. Because of its diverse effects on eosinophils, IL-5 is strongly implicated in the pathogenesis of asthma and other hypereosinophilic inflammatory conditions (4-6). Mouse IL-5 cDNA encodes a 133 amino acid (aa) residue precursor protein containing a hydrophobic signal peptide that is cleaved to yield a 113 aa residue mature protein. Native mouse IL-5 is a disulfide-linked homodimeric 40-45 kDa glycoprotein with N- and O-linked carbohydrate chains. Mature human IL-5 is approximately 70 % identical at the amino acid level to mouse IL-5. Whereas mouse and human IL-5 are equally active on human cell lines, human IL-5 is much less active than mouse IL-5 in mouse cell assays (1-3). IL-5 is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes.
    途径
    JAK/STAT Signaling, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
You are here:
客服