IL-22 ELISA 试剂盒
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- 抗原 See all IL-22 (IL22) ELISA试剂盒
- IL-22 (IL22) (Interleukin 22 (IL22))
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适用
- 人
- 检测方法
- Colorimetric
- 实验类型
- Sandwich ELISA
- 检测范围
- 31.25-2000 pg/mL
- 最低检测浓度
- 31.25 pg/mL
- 应用范围
- ELISA
- 样品类型
- Cell Culture Supernatant, Serum, Plasma (heparin), Plasma (citrate), Plasma (EDTA)
- Analytical Method
- Quantitative
- 特异性
- Natural and recombinant Human IL-22 Ligand
- 灵敏度
- 15 pg/mL
- 试剂未包括
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- Microplate reader.
- Pipettes and pipette tips.
- EP tube Deionized or distilled water.
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- Discover our best selling IL22 ELISA Kit
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- Discover our top product IL22 ELISA Kit
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Interleukin 22 (IL22) ELISA Kit
IL22 适用: 人 Colorimetric Sandwich ELISA 7.8 pg/mL - 500 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 22 (IL22) ELISA KitIL22 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cerebrospinal Fluid, Plasma, Serum, Urine
Interleukin 22 (IL22) ELISA KitIL22 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 22 (IL22) ELISA KitSmall Sample IL22 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 22 (IL22) ELISA KitIL22 适用: Pig Colorimetric Sandwich ELISA 46.875 pg/mL - 3000 pg/mL Plasma, Serum, Tissue Homogenate
Interleukin 22 (IL22) ELISA KitIL22 适用: 大鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 22 (IL22) ELISA KitIL22 适用: Cow Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Cell Lysate, Plasma, Serum, Tissue Homogenate
Interleukin 22 (IL22) ELISA KitIL22 适用: 人 AA 34-179 Colorimetric Sandwich ELISA 15.6-1000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Interleukin 22 (IL22) ELISA KitIL22 适用: 人 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
Interleukin 22 (IL22) ELISA KitIL22 适用: Pig Colorimetric Sandwich ELISA 20-6.000 pg/mL Cell Culture Supernatant, Plasma, Serum
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- 应用备注
- Detection Wavelength: 450 nm
- 样本量
- 20 μL
- 实验时间
- 3 h
- 板类型
- Pre-coated
- 限制
- 仅限研究用
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- 储存条件
- 4 °C
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- 抗原 See all IL-22 (IL22) ELISA试剂盒
- IL-22 (IL22) (Interleukin 22 (IL22))
- 别名
- IL-22 (IL22 产品)
- 别名
- IL-21 ELISA Kit, IL-22 ELISA Kit, IL-D110 ELISA Kit, IL-TIF ELISA Kit, ILTIF ELISA Kit, TIFIL-23 ELISA Kit, TIFa ELISA Kit, zcyto18 ELISA Kit, IL-22a ELISA Kit, ILTIFa ELISA Kit, Iltif ELISA Kit, RGD1561292 ELISA Kit, interleukin-22 ELISA Kit, interleukin 22 ELISA Kit, IL22 ELISA Kit, il22 ELISA Kit, Il22 ELISA Kit
- 背景
- Interleukin 22 (IL-22), also known as IL-10-related T cell-derived inducible factor (IL-TIF), is a member of the IL-10 cytokine family. Other members of this family include IL-10, IL-19, IL-20, IL-24, and IL-26 (1). IL-22 was initially identified as a gene induced by IL-9 in mouse T cells and mast cells (2). Human IL-22 cDNA encodes a 179 amino acid (aa) protein with a putative 33 aa signal peptide, sharing approximately 79 % and 22 % aa sequence identity with mouse IL-22 and human IL-10, respectively (3, 4). Although the related IL-10 is thought to act as a dimer, the crystal structure of IL-22 suggests it may interact with its receptor as a monomer (5). The functional IL-22 receptor is of the class 2 subtype and consists of two receptor subunits,IL-22 R (previously an orphan receptor named CRF2-9) and IL-10 R (previously known as CRF2-4) (6). The IL-10 R chain is shared by IL-10, IL-26, IL-28A, IL-28B, and IL-29 (7, 8).IL-22 R is expressed primarily in the pancreas, and to a lesser extent, tissues of the gastrointestinal tract, kidney, and skin (7, 9 - 12). A soluble receptor, IL-22 binding protein (IL-22BP), has also been described and may act as an endogenous inhibitor of IL-22 activity (13 - 15). IL-22 has been shown to activate Jak/STAT and MAPK signaling pathways and upregulate the production of acute phase proteins (3, 4, 6, 16 - 18).IL-22 is produced primarily by activated Th1-type T cells and NK cells (19). Mouse IL-22 expression is induced in various organs upon lipopolysaccharide injection, suggesting that it may be involved in inflammatory responses (3). In humans, this is supported by the observation that IL-22 is produced by synovial fibroblasts and macrophages of rheumatoid arthritis (RA) patients and is capable of inducing pro-inflammatory responses in RA synovial tissues (20). In addition, it stimulates the production of pro-inflammatory cytokines and anti-microbial defensins in human keratinocytes (9, 10). These activities result in epidermal hyperplasia in models of human skin (9).
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