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- 抗原 See all MME 试剂盒
- MME (Membrane Metallo-Endopeptidase (MME))
- 检测方法
- Fluorometric
- 应用范围
- Activation (Act), Fluorescence Resonance Energy Transfer Microscopy (FRET)
- 品牌
- SensoLyte®
- 产品特性
- The SensoLyte® 520 Neprilysin Assay Kit employs a novel internally quenched 5-FAM/QXL™ FRET substrate for the detection of neprilysin activity. The enzyme cleaves the FRET substrate into two separate fragments resulting in the release of 5-FAM fluorescence, which can be monitored at excitation /emission= 490/520 nm. The long wavelength fluorescence of 5-FAM is less interfered by the autofluorescence of components in biological samples and test compounds. The assay can detect as low as 0.78 ng/mL of active neprilysin.
- Top Product
- Discover our top product MME ELISA Kit
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Membrane Metallo-Endopeptidase (MME) ELISA Kit
MME 适用: 人 Colorimetric Sandwich ELISA 31.2 pg/mL - 2000 pg/mL Cell Culture Supernatant, Cell Lysate, Cerebrospinal Fluid, Plasma, Serum, Tissue Homogenate
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 大鼠 Colorimetric Sandwich ELISA 78 pg/mL - 5000 pg/mL Plasma, Serum, Tissue Homogenate
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 人 Colorimetric Sandwich ELISA 0.16 ng/mL - 10 ng/mL Cell Culture Supernatant, Plasma, Serum
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 小鼠 Colorimetric Sandwich ELISA 15.6 pg/mL - 1000 pg/mL Plasma, Serum, Tissue Homogenate
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 人 AA 52-750 Colorimetric Sandwich ELISA 125-8000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 小鼠 AA 52-750 Colorimetric Sandwich ELISA 93.7-6000 pg/mL Cell Culture Supernatant, Plasma (EDTA), Plasma (heparin), Serum
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 小鼠 Colorimetric Sandwich ELISA 78.125 pg/mL - 5000 pg/mL Plasma, Serum
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 小鼠 Colorimetric Sandwich ELISA 61-15000 pg/mL Cell Culture Supernatant, Plasma, Serum
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 人 Colorimetric Sandwich ELISA 125 pg/mL - 8000 pg/mL Cell Culture Supernatant, Plasma (EDTA - heparin), Serum
Membrane Metallo-Endopeptidase (MME) ELISA KitMME 适用: 人 Colorimetric Sandwich ELISA 125-8000 pg/mL Cell Culture Supernatant, Plasma, Serum
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- 说明
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FRET-based Assay Kit
- 限制
- 仅限研究用
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- 注意事项
- Protect Components A abd B from light and moisture.
- 储存条件
- -80 °C
- 储存方法
- Store all kit Components at -20 °C, except Component C, which should be stored at -80 °C.
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- 抗原
- MME (Membrane Metallo-Endopeptidase (MME))
- 别名
- Neprilysin (MME 产品)
- 物质类
- Chemical
- 背景
- Neprilysin (NEP) is a transmembrane metallopeptidase normally expressed by a variety of tissues. It is also known as neutral endopeptidase, and enkephalinase. NEP cleaves peptides at the N-terminal side of hydrophobic amino acid residues and is responsible for the degradation and inactivation of a variety of physiological substrates. NEP is a major extracellular amyloid beta-peptide degrading enzyme in the brain and targeting NEP is considered a potential therapeutic strategy for the prevention and treatment of Alzheimer's disease. NEP has also been implicated in the pathogenesis of hypertension, diabetes, and cancer.
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