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- 抗原 See all MMP3 试剂盒
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
- 检测方法
- Fluorometric
- 应用范围
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- 品牌
- SensoLyte®
- 产品特性
- SensoLyte® 520 MMP-3 Assay Kit uses a 5-FAM (fluorophore) and QXL520™ (quencher) labeled FRET peptide substrates for continuous measurement of the enzyme activities. This substrate showed excellent specificity to MMP-3 with minimal cross-reaction with MMP-1, 2, 7, 8, 9, 13 and 14. In an intact FRET peptide, the fluorescence of 5-FAM is quenched by QXL520™. Upon the cleavage of the FRET peptide by MMP-3, the fluorescence of 5-FAM is recovered, and can be continuously monitored at excitation/emission = 490 nm/520 nm. With superior fluorescence quantum yield and longer emission wavelength, 5-FAM/QXL520™ based FRET peptide is less interfered by the autofluorescence of test compounds and cellular components and provides better assay sensitivity.
- Top Product
- Discover our top product MMP3 ELISA Kit
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- 说明
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FRET-based Assay Kit
- 限制
- 仅限研究用
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- 注意事项
- Protect Components A and B from light.
- 储存条件
- -20 °C
- 储存方法
- Store all components at -20 °C. Components D and E can be stored at 4 °C for convenience.
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IL-1?-induced, matrix metalloproteinase-3-regulated proliferation of embryonic stem cell-derived odontoblastic cells is mediated by the Wnt5 signaling pathway." in: Experimental cell research, Vol. 328, Issue 1, pp. 69-86, (2014) (PubMed).
: "Matrix metalloproteinase content and activity in low-platelet, low-leukocyte and high-platelet, high-leukocyte platelet rich plasma (PRP) and the biologic response to PRP by human ligament ..." in: The American journal of sports medicine, Vol. 42, Issue 5, pp. 1211-8, (2014) (PubMed).
: "Proinflammatory cytokines induce stromelysin-1-mediated cell proliferation in dental pulp fibroblast-like cells." in: Journal of endodontics, Vol. 40, Issue 1, pp. 89-94, (2013) (PubMed).
: "Matrix metalloproteinase-3 is activated by HtrA2/Omi in dopaminergic cells: relevance to Parkinson's disease." in: Neurochemistry international, Vol. 60, Issue 3, pp. 249-56, (2012) (PubMed).
: "Liver regeneration associated protein (ALR) exhibits antimetastatic potential in hepatocellular carcinoma." in: Molecular medicine (Cambridge, Mass.), Vol. 17, Issue 3-4, pp. 221-8, (2011) (PubMed).
: "Endothelins stimulate the production of stromelysin-1 in cultured rat astrocytes." in: Biochemical and biophysical research communications, Vol. 371, Issue 4, pp. 659-63, (2008) (PubMed).
: "Inhibition of MMP-3 or -9 suppresses lipopolysaccharide-induced expression of proinflammatory cytokines and iNOS in microglia." in: Journal of neurochemistry, Vol. 106, Issue 2, pp. 770-80, (2008) (PubMed).
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IL-1?-induced, matrix metalloproteinase-3-regulated proliferation of embryonic stem cell-derived odontoblastic cells is mediated by the Wnt5 signaling pathway." in: Experimental cell research, Vol. 328, Issue 1, pp. 69-86, (2014) (PubMed).
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- 抗原
- MMP3 (Matrix Metallopeptidase 3 (Stromelysin 1, Progelatinase) (MMP3))
- 别名
- MMP-3 (MMP3 产品)
- 别名
- CHDS6 Kit, MMP-3 Kit, SL-1 Kit, STMY Kit, STMY1 Kit, STR1 Kit, SLN-1 Kit, SLN1 Kit, STR-1 Kit, Stmy1 Kit, Str1 Kit, MMP10 Kit, chds6 Kit, mmp-3 Kit, mmp13 Kit, mmp3 Kit, sl-1 Kit, stmy Kit, stmy1 Kit, str1 Kit, matrix metallopeptidase 3 Kit, matrix metallopeptidase 3 (stromelysin 1, progelatinase) Kit, matrix metallopeptidase 3 L homeolog Kit, MMP3 Kit, Mmp3 Kit, mmp3.L Kit
- 背景
- Matrix metalloproteinases (MMPs) belong to a family of secreted or membrane-associated proteins capable of digesting extracellular matrix components. The importance of MMPs in tumor development and invasion and other diseases is well known. MMP-3 (stromelysin-1, transin-1) is proposed as a potential therapeutic target.
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