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- 抗原 See all MMP1 试剂盒
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 检测方法
- Fluorometric
- 应用范围
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- 品牌
- SensoLyte®
- 产品特性
- SensoLyte® 520 MMP-1 Assay Kit uses a 5-FAM (fluorophore) and QXL520™ (quencher) labeled FRET peptide substrate for continuous measurement of enzyme activity. In an intact FRET peptide, the fluorescence of 5-FAM is quenched by QXL520™. Upon the cleavage of the FRET peptide by MMP-1, the fluorescence of 5-FAM is recovered, and can be continuously monitored at excitation/emission = 490 nm/520 nm. With superior fluorescence quantum yield and longer emission wavelength, 5-FAM/QXL520™ based FRET peptide has less interference from the autofluorescence of test compounds and cellular components and provides better assay sensitivity. The assays are performed in a convenient 96-well or 384-well microplate format.
- Top Product
- Discover our top product MMP1 ELISA Kit
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- 说明
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FRET-based Assay Kit
- 限制
- 仅限研究用
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- 注意事项
- Protect Components A and B from light.
- 储存条件
- -20 °C
- 储存方法
- Store all components at -20 °C. Components D and E can be stored at 4 °C for convenience.
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Matrix metalloproteinase (MMP)-1 induces lung alveolar epithelial cell migration and proliferation, protects from apoptosis, and represses mitochondrial oxygen consumption." in: The Journal of biological chemistry, Vol. 288, Issue 36, pp. 25964-75, (2013) (PubMed).
: "Liver regeneration associated protein (ALR) exhibits antimetastatic potential in hepatocellular carcinoma." in: Molecular medicine (Cambridge, Mass.), Vol. 17, Issue 3-4, pp. 221-8, (2011) (PubMed).
: "Matrix metalloproteinase-1 induces cleavage of exogenous alphaB-crystallin transduced by a cell-penetrating peptide." in: Journal of cellular biochemistry, Vol. 112, Issue 9, pp. 2454-62, (2011) (PubMed).
: "Development of a gene therapy virus with a glucocorticoid-inducible MMP1 for the treatment of steroid glaucoma." in: Investigative ophthalmology & visual science, Vol. 51, Issue 6, pp. 3029-41, (2010) (PubMed).
: "Inhibition of ceramide-redox signaling pathway blocks glomerular injury in hyperhomocysteinemic rats." in: Kidney international, Vol. 70, Issue 1, pp. 88-96, (2006) (PubMed).
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Matrix metalloproteinase (MMP)-1 induces lung alveolar epithelial cell migration and proliferation, protects from apoptosis, and represses mitochondrial oxygen consumption." in: The Journal of biological chemistry, Vol. 288, Issue 36, pp. 25964-75, (2013) (PubMed).
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- 抗原
- MMP1 (Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1))
- 别名
- MMP-1 (MMP1 产品)
- 别名
- CLG Kit, CLGN Kit, Mmp1a Kit, CG4859 Kit, Dm1-MMP Kit, Dmel\\CG4859 Kit, MMP-1 Kit, MMP1 Kit, Mmp 1 Kit, dMMP1 Kit, dm1-MMP Kit, dmmp1 Kit, l(2)k04809 Kit, mmp1 Kit, Mmp1 Kit, Mcol-A Kit, Mcola Kit, col4 Kit, mmp18 Kit, Clgn Kit, matrix metallopeptidase 1 Kit, Matrix metalloproteinase 1 Kit, matrix metalloproteinase 1 Kit, matrix metallopeptidase 1 (interstitial collagenase) Kit, matrix metallopeptidase 1a (interstitial collagenase) Kit, matrix metallopeptidase 1 S homeolog Kit, interstitial collagenase Kit, matrix metallopeptidase 8 L homeolog Kit, MMP1 Kit, Mmp1 Kit, RB11133 Kit, Mmp1a Kit, mmp1.S Kit, LOC100727966 Kit, mmp8.L Kit
- 背景
- MMP-1 (interstitial collagenase, fibroblast collagenase) is an extracellular protease. This enzyme plays a significant role in cancer, arthritis and other diseases, and has been identified as a drug-screening target.
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