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- 抗原 See all Cathepsin G (CTSG) 试剂盒
- Cathepsin G (CTSG)
- 检测方法
- Fluorometric
- 应用范围
- Fluorescence Resonance Energy Transfer Microscopy (FRET)
- 品牌
- SensoLyte®
- 产品特性
- The SensoLyte® 520 Cathepsin G Activity Assay Kit uses a HiLyte Fluor™ 488/QXL™ 520 FRET peptide substrate for the measurement of enzyme activity. In the intact FRET peptide, the fluorescence of HiLyte Fluor™ 488 is quenched by QXL™ 520. Upon cleavage of the FRET peptide by the active enzyme, the increase of fluorescence can be continuously monitored at excitation/emission = 490/520 nm. With superior fluorescence quantum yield and longer emission wavelength, the HiLyte Fluor™ 488/QXL™ 520 based FRET peptide has less interference from the autofluorescence of test compounds and cellular components and provides better assay sensitivity. The fluorescent signal from HiLyte Fluor™ 488 is stable at low pH, which is the optimal pH for cathepsin activity. The kit can be used to detect the activity of Cathepsin G enzyme in biological samples and purified enzyme preparations.
- Top Product
- Discover our top product CTSG ELISA Kit
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- 说明
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FRET-based Assay Kit
- 限制
- 仅限研究用
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- 注意事项
- Protect Components A and B from light and moisture.
- 储存条件
- -80 °C
- 储存方法
- Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
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Serine protease inhibitor A3 in atherosclerosis and aneurysm disease." in: International journal of molecular medicine, Vol. 30, Issue 2, pp. 288-94, (2012) (PubMed).
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Serine protease inhibitor A3 in atherosclerosis and aneurysm disease." in: International journal of molecular medicine, Vol. 30, Issue 2, pp. 288-94, (2012) (PubMed).
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- 抗原
- Cathepsin G (CTSG)
- 别名
- Cathepsin G (CTSG 产品)
- 别名
- CATG Kit, CG Kit, CTSG Kit, Ctsg Kit, cathepsin G Kit, CTSG Kit, Ctsg Kit, LOC505658 Kit, LOC509956 Kit, ctsg Kit, LOC100053921 Kit, LOC102174648 Kit, LOC100733619 Kit, LOC100154047 Kit
- 背景
- Cathepsins are a class of globular lysosomal proteases playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin G is the serine protease released by neutrophils upon their activation. Cathepsin G is currently being explored as a target for anti-inflammatory and anti-infective drugs.
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