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SensoLyte® 390 Cathepsin D Assay Kit

FRET Fluorometric
产品编号 ABIN1882438
发货至: 中国
  • 抗原 See all Cathepsin D (CTSD) 试剂盒
    Cathepsin D (CTSD)
    检测方法
    Fluorometric
    应用范围
    Fluorescence Resonance Energy Transfer Microscopy (FRET)
    品牌
    SensoLyte®
    产品特性
    The SensoLyte® 390 Cathepsin D Activity Assay Kit uses a Mca/Dnp FRET peptide for measurement of enzyme activity. In the FRET peptide, the fluorescence of Mca is quenched by Dnp. Upon cleavage into two separate fragments by Cathepsin D, the fluorescence of Mca is recovered, and can be monitored at excitation/emission = 330 nm/390 nm.
    Top Product
    Discover our top product CTSD ELISA Kit
  • 说明

    FRET-based Assay Kit

    限制
    仅限研究用
  • 注意事项
    Protect Components A and B from light and moisture.
    储存条件
    -80 °C
    储存方法
    Store all kit components at -20 °C, except for Component C. Store Component C at -80 °C. Component D can be stored at room temperature for convenience
  • Poliakov, Strunnikova, Jiang, Martinez, Parikh, Lakkaraju, Thomas, Brooks, Redmond: "Multiple A2E treatments lead to melanization of rod outer segment-challenged ARPE-19 cells." in: Molecular vision, Vol. 20, pp. 285-300, (2014) (PubMed).

  • 抗原
    Cathepsin D (CTSD)
    别名
    Cathepsin D (CTSD 产品)
    别名
    catD Kit, fb93e11 Kit, fj17b09 Kit, wu:fb93e11 Kit, wu:fj17b09 Kit, LOC398557 Kit, Cathd Kit, CatD Kit, LOC100136761 Kit, CTSD Kit, DKFZp469J0315 Kit, DDBDRAFT_0205785 Kit, DDBDRAFT_0215012 Kit, DDB_0205785 Kit, DDB_0215012 Kit, CLN10 Kit, CPSD Kit, CD Kit, cathepsin D Kit, cathepsin D S homeolog Kit, lysosomal aspartic protease Kit, cathepsin D-like Kit, ctsd Kit, LOC398557 Kit, ctsd.S Kit, CatD Kit, LOC5567565 Kit, LOC100136761 Kit, CTSD Kit, Cathd Kit, ctsD Kit, catd Kit, Ctsd Kit, LOC443060 Kit
    背景
    Cathepsins are a class of globular lysosomal proteases, playing a vital role in mammalian cellular turnover. They degrade polypeptides and are distinguished by their substrate specificities. Cathepsin D is the lysosomal aspartic proteinase, active in intracellular protein breakdown. It is involved in the pathogenesis of several diseases such as breast cancer and Alzheimer disease.
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