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KIR2DS4 蛋白

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Short Cytoplasmic Tail, 4 (KIR2DS4))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
KIR2DS4 蛋白 KIR2DS4 蛋白 KIR2DS4 蛋白 (ABIN934899)

KIR2DS4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 95 % pure SDS

KIR2DS4 Protein (AA 22-302) (His tag) (ABIN7403051)

KIR2DS4 宿主: 人 宿主: 大肠杆菌(E. Coli) Recombinant > 90 % SDS, WB, Imm, PC

KIR2DS4 蛋白 by Origin

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KIR2DS4 蛋白 by Source

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KIR2DS4 蛋白 by 蛋白类型

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KIR2DS4 蛋白 by 应用范围

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Popular KIR2DS4 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN934899
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7403051
Quantity 100 μg
Datasheet Datasheet

Aliases for KIR2DS4 蛋白

killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 4 (KIR2DS4) 蛋白
CD158I 蛋白
KIR1D 蛋白
KIR412 蛋白
KKA3 蛋白
NKAT8 蛋白
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