KIR2DS2 产品
(Killer Cell Immunoglobulin-Like Receptor 2DS2 (KIR2DS2))
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Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Featured KIR2DS2 Categories
KIR2DS2 抗体
High quality antibodies with extensive validation data.
KIR2DS2 蛋白
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended KIR2DS2 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7157511
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, ICC
Validations
- (3)
Cat. No.
ABIN1859539
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS, IHC (p)
Validations
- (3)
Cat. No.
ABIN651951
Quantity
400 μL
Datasheet
Datasheet
Recommended KIR2DS2 蛋白
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7403846
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN3010362
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN2724252
Quantity
20 μg
Datasheet
Datasheet
Synonyms and alternative names related to KIR2DS2
killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2 (KIR2DS2), 183ActI, CD158b, CD158J, cl-49, NKAT5Protein level used designations for KIR2DS2
- 1060P11.9.2
- CD158 antigen-like family member J
- MHC class I NK cell receptor
- NK receptor 183 ActI
- NKAT-5
- killer cell immunoglobulin-like receptor 2DS2
- killer-cell Ig-like receptor
- killer-cell immunoglobulin-like receptor two domains short tail 2 protein
- natural killer associated transcript 5
- natural killer cell inhibitory receptor
- natural killer-associated transcript 5
- p58 KIR
- p58 NK receptor CL-49
- p58 killer cell inhibitory receptor KIR-K7a
- p58 natural killer cell receptor clone CL-49
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