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KIR2DL4/CD158d 抗体

(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 4 (KIR2DL4))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. This gene is one of the 'framework' loci that is present on all haplotypes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008].
KIR2DL4/CD158d 抗体 KIR2DL4/CD158d 抗体 KIR2DL4/CD158d 抗体 (ABIN509568)

KIR2DL4 适用: 人 WB, FACS, IP, ICC 宿主: 小鼠 Monoclonal mAb 33 unconjugated

KIR2DL4/CD158d 抗体 KIR2DL4/CD158d 抗体 KIR2DL4/CD158d 抗体 (ABIN1302514)

KIR2DL4 适用: 人 WB, FACS, IP, ICC, Func 宿主: 小鼠 Monoclonal mAb 33 unconjugated

KIR2DL4/CD158d 抗体  (AA 22-120) KIR2DL4/CD158d 抗体  (AA 22-120) KIR2DL4/CD158d 抗体 (AA 22-120) (ABIN7193292)

KIR2DL4 适用: 人 WB, FACS, ELISA, IHC, ICC, Neut 宿主: 小鼠 Monoclonal 4C2D11 unconjugated

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Find KIR2DL4/CD158d 抗体 for a variety of species such as anti-Human KIR2DL4/CD158d, anti-Mouse KIR2DL4/CD158d, anti-Rat KIR2DL4/CD158d. The species listed below are among those available. Click on a link to go to the corresponding products.

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Find KIR2DL4/CD158d 抗体 with a specific epitope. The epitopes listed below are among those available. Click on a link to go to the corresponding products.

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Find KIR2DL4/CD158d 抗体 with a specific conjugate such as PE, APC, Biotin. The conjugates listed below are among those available. Click on a link to go to the corresponding products.

Popular KIR2DL4/CD158d 抗体

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Reactivity
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Validations
Cat. No.
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Datasheet
Reactivity Human
Application WB, FACS, IP, ICC
Validations
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Cat. No. ABIN509568
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IP, ICC, Func
Validations
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Cat. No. ABIN1302514
Quantity 0.1 mg
Datasheet Datasheet
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Application WB, FACS, ELISA, IHC, ICC, Neut
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Application WB, ICC, IHC (p), IF
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Quantity 100 μL
Datasheet Datasheet
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Application WB, FACS, IHC (p)
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Cat. No. ABIN652985
Quantity 400 μL
Datasheet Datasheet
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Cat. No. ABIN489933
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Datasheet Datasheet
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Application WB, FACS, IHC (p), EIA
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Cat. No. ABIN951198
Quantity 0.4 mL
Datasheet Datasheet
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Application WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
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Cat. No. ABIN748463
Quantity 100 μL
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Datasheet Datasheet
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Datasheet Datasheet
Reactivity Human
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  • (1)
Cat. No. ABIN6142882
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p), IHC (fro)
Validations
Cat. No. ABIN748465
Quantity 100 μL
Datasheet Datasheet

Latest Publications for our KIR2DL4/CD158d 抗体

Ueshima, Kataoka, Hirata, Sugimoto, Iemura, Minamiguchi, Nomura, Haga: "Possible Involvement of Human Mast Cells in the Establishment of Pregnancy via Killer Cell Ig-Like Receptor 2DL4." in: The American journal of pathology, Vol. 188, Issue 6, pp. 1497-1508, (2019) (PubMed).

Takei, Ueshima, Kataoka, Hirata, Sugimoto, Rokutan-Kurata, Moriyoshi, Ono, Murakami, Iwamoto, Haga: "Killer cell immunoglobulin-like receptor 2DL4 is expressed in and suppresses the cell growth of Langerhans cell histiocytosis." in: Oncotarget, Vol. 8, Issue 23, pp. 36964-36972, (2017) (PubMed).

Kennedy, Chazara, Gardner, Ivarsson, Farrell, Xiong, Hiby, Colucci, Sharkey, Moffett: "Activating KIR2DS4 Is Expressed by Uterine NK Cells and Contributes to Successful Pregnancy." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 11, pp. 4292-4300, (2017) (PubMed).

Wi?niewski, Kowal, Wyrodek, Nowak, Majorczyk, Wagner, Pawlak-Adamska, Jankowska, ?lesak, Frydecka, Ku?nierczyk: "Genetic polymorphisms and expression of HLA-G and its receptors, KIR2DL4 and LILRB1, in non-small cell lung cancer." in: Tissue antigens, Vol. 85, Issue 6, pp. 466-75, (2015) (PubMed).

Dunphy, Guinan, Chorcora, Jayaraman, Traherne, Trowsdale, Pende, Middleton, Gardiner: "2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells." in: Genes and immunity, Vol. 16, Issue 5, pp. 301-10, (2015) (PubMed).

Siewiera, El Costa, Tabiasco, Berrebi, Cartron, Le Bouteiller, Bouteiller, Jabrane-Ferrat: "Human cytomegalovirus infection elicits new decidual natural killer cell effector functions." in: PLoS pathogens, Vol. 9, Issue 4, pp. e1003257, (2014) (PubMed).

Le Page, Goodridge, John, Christiansen, Witt: "Killer Ig-like receptor 2DL4 does not mediate NK cell IFN-? responses to soluble HLA-G preparations." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 2, pp. 732-40, (2014) (PubMed).

Rajagopalan, Lee, DuPrie, Long: "TNFR-associated factor 6 and TGF-β-activated kinase 1 control signals for a senescence response by an endosomal NK cell receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 2, pp. 714-21, (2014) (PubMed).

Baudhuin, Lesport, Sousa, Migraine, Vigneron, Lemaoult, Carosella, Mooney, Favier: "HLA-G inhibition of NK-cell cytolytic function is uncoupled from tumor cell lipid raft reorganization." in: European journal of immunology, Vol. 42, Issue 3, pp. 700-9, (2012) (PubMed).

Liu, Chen, Richardson: "Decreased DNA methyltransferase levels contribute to abnormal gene expression in "senescent" CD4(+)CD28(-) T cells." in: Clinical immunology (Orlando, Fla.), Vol. 132, Issue 2, pp. 257-65, (2009) (PubMed).

Aliases for KIR2DL4/CD158d 抗体

killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 4 (KIR2DL4) 抗体
killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 4 (KIR2DL4) 抗体
CD158D 抗体
G9P 抗体
KIR2DL4 抗体
KIR103 抗体
KIR103AS 抗体
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