KIR2DL1 抗体
(Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 1 (KIR2DL1))
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several 'framework' genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules\\\\; thus, KIR proteins are thought to play an important role in regulation of the immune response. [provided by RefSeq, Jul 2008].
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Find KIR2DL1 抗体 for a variety of species such as anti-Human KIR2DL1, anti-Mouse KIR2DL1, anti-Monkey KIR2DL1. The species listed below are among those available. Click on a link to go to the corresponding products.
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Latest Publications for our KIR2DL1 抗体
: "Eomesodermin and T-bet mark developmentally distinct human natural killer cells." in: JCI insight, Vol. 2, Issue 5, pp. e90063, (2017) (PubMed).: "NK Cell Responses to Human Tick-Borne Encephalitis Virus Infection." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 197, Issue 7, pp. 2762-71, (2016) (PubMed).
: "New insights on the natural killer cell repertoire from a thorough analysis of cord blood cells." in: Journal of leukocyte biology, Vol. 100, Issue 3, pp. 471-9, (2016) (PubMed).
: "Regulation of Adaptive NK Cells and CD8 T Cells by HLA-C Correlates with Allogeneic Hematopoietic Cell Transplantation and with Cytomegalovirus Reactivation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 9, pp. 4524-36, (2015) (PubMed).
: "The Human NK Cell Response to Yellow Fever Virus 17D Is Primarily Governed by NK Cell Differentiation Independently of NK Cell Education." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3262-72, (2015) (PubMed).
: "2DL1, 2DL2 and 2DL3 all contribute to KIR phenotype variability on human NK cells." in: Genes and immunity, Vol. 16, Issue 5, pp. 301-10, (2015) (PubMed).
: "Uptake of CCR7 by KIR2DS4⁺ NK cells is induced upon recognition of certain HLA-C alleles." in: Journal of immunology research, Vol. 2015, pp. 754373, (2015) (PubMed).
: "Tissue-Specific Education of Decidual NK Cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3026-32, (2015) (PubMed).
: "Coordinated expression of DNAM-1 and LFA-1 in educated NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 9, pp. 4518-27, (2015) (PubMed).
: "Cutting edge: identification and characterization of human intrahepatic CD49a+ NK cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 6, pp. 2467-71, (2015) (PubMed).
Aliases for KIR2DL1 抗体
killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 1 (KIR2DL1) 抗体killer cell immunoglobulin-like receptor, two domains, long cytoplasmic tail, 1 (KIR2DL1) 抗体
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