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KHDC3 蛋白

(KH Domain Containing 3, Subcortical Maternal Complex Member (KHDC3))
Required for maintenance of euploidy during cleavage- stage embryogenesis. Ensures proper spindle assembly by regulating the localization of AURKA via RHOA signaling and of PLK1 via a RHOA-independent process. Required for the localization of MAD2L1 to kinetochores to enable spindle assembly checkpoint function (By similarity).

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Synonyms and alternative names related to KHDC3

KH domain containing 3, subcortical maternal complex member (Khdc3), 2410004A20Rik, AI467128, Ecat1, FILIA, OEEP48, RGD1311617

Protein level used designations for KHDC3

  • ES cell associated transcript 1
  • ES cell-associated transcript 1 protein
  • KH domain-containing protein 3
  • protein Filia
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