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Kdm6b 产品

(Lysine (K)-Specific Demethylase 6B (Kdm6b))
Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Involved in inflammatory response by participating in macrophage differentiation in case of inflammation by regulating gene expression and macrophage differentiation.

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Featured Kdm6b Categories

Kdm6b 抗体

High quality antibodies with extensive validation data.

Kdm6b ELISA试剂盒

Reliable ELISA kits for a wide range of species.

Recommended Kdm6b 抗体

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Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IF
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Cat. No. ABIN6142806
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IF, IHC (p)
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Cat. No. ABIN387862
Quantity 200 μL
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Reactivity Human
Application WB, ELISA, IF, IHC
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Cat. No. ABIN3031660
Quantity 0.2 mL
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Recommended Kdm6b ELISA试剂盒

Product
Reactivity
Analytical Method
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Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6957577
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Sandwich ELISA
Validations
Cat. No. ABIN422442
Quantity 96 tests
Datasheet Datasheet

Latest Publications for our Kdm6b Products

Liu, Wang, Pan, Wu, Yang, Qin, Jia, Xiao, Long, Ge, Liu, Zhu: "Endogenous hydrogen sulfide regulates histone demethylase JMJD3-mediated inflammatory response in LPS-stimulated macrophages and in a mouse model of LPS-induced septic shock." in: Biochemical pharmacology, Vol. 149, pp. 153-162, (2018) (PubMed).

Luo, Yang, Wu, Long, Xiao, Qin, Law, Suguro, Xu, Qu, Liu, Zhu: "Critical role of histone demethylase Jumonji domain-containing protein 3 in the regulation of neointima formation following vascular injury." in: Cardiovascular research, Vol. 114, Issue 14, pp. 1894-1906, (2018) (PubMed).

Luo, Dunphy, McBride: "Ehrlichia chaffeensis Tandem Repeat Effector Targets Differentially Influence Infection." in: Frontiers in cellular and infection microbiology, Vol. 7, pp. 178, (2017) (PubMed).

Angrisano, Pero, Brancaccio, Coretti, Florio, Pezone, Calabrò, Falco, Keller, Lembo, Avvedimento, Chiariotti: "Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells." in: PLoS ONE, Vol. 11, Issue 6, pp. e0156671, (2017) (PubMed).

Petruk, Mariani, De Dominici, Porazzi, Minieri, Cai, Iacovitti, Flomenberg, Calabretta, Mazo: "Structure of Nascent Chromatin Is Essential for Hematopoietic Lineage Specification." in: Cell reports, Vol. 19, Issue 2, pp. 295-306, (2017) (PubMed).

Liao, Kuo, Lu, Wang, Wu: "Generation of an anti-EpCAM antibody and epigenetic regulation of EpCAM in colorectal cancer." in: International journal of oncology, Vol. 46, Issue 4, pp. 1788-800, (2015) (PubMed).

Hashizume, Andor, Ihara, Lerner, Gan, Chen, Fang, Huang, Tom, Ngo, Solomon, Mueller, Paris, Zhang, Petritsch, Gupta, Waldman, James: "Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma." in: Nature medicine, (2014) (PubMed).

Lee, Na, Lee, Na, Cho, Wu, Yune, Kim, Ju: "Molecular mechanism of Jmjd3-mediated interleukin-6 gene regulation in endothelial cells underlying spinal cord injury." in: Journal of neurochemistry, Vol. 122, Issue 2, pp. 272-82, (2013) (PubMed).

Pham, Yu, Walline, Muthukrishnan, Blum, Kaplan: "Opposing roles of STAT4 and Dnmt3a in Th1 gene regulation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 2, pp. 902-11, (2013) (PubMed).

Ramadoss, Chen, Wang: "Histone demethylase KDM6B promotes epithelial-mesenchymal transition." in: The Journal of biological chemistry, Vol. 287, Issue 53, pp. 44508-17, (2012) (PubMed).

Synonyms and alternative names related to Kdm6b

lysine (K)-specific demethylase 6B (kdm6b), lysine demethylase 6B (KDM6B), lysine (K)-specific demethylase 6B, b (kdm6bb), KDM1 lysine (K)-specific demethylase 6B (Kdm6b), lysine demethylase 6B (Kdm6b), 1700064E03Rik, BC038313, jmjd3, Jmjd3, JMJD3, kdm6b, mKIAA0346, si:ch211-237l4.7

Protein level used designations for Kdm6b

  • jumonji domain containing 3
  • lysine (K)-specific demethylase 6B
  • jumonji domain containing 3, histone lysine demethylase
  • lysine-specific demethylase 6B-like
  • jmjC domain-containing protein 3
  • jumonji domain-containing protein 3
  • lysine-specific demethylase 6B
  • lysine demethylase 6B
  • jumonji domain-containing 3
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