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KDM4B 产品

(Lysine (K)-Specific Demethylase 4B (KDM4B))

Categories

Histone demethylase that specifically demethylates 'Lys- 9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

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Featured KDM4B Categories

KDM4B 抗体

High quality antibodies with extensive validation data.

KDM4B 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KDM4B 抗体

Product
Reactivity
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Cat. No.
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Datasheet
Reactivity Human
Application WB, IF, IP
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Cat. No. ABIN7268329
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
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Cat. No. ABIN5611347
Quantity 100 μL
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  • (3)
Cat. No. ABIN6972226
Quantity 100 μL
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Recommended KDM4B 蛋白

Product
Reactivity
Source
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Cat. No.
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Reactivity Human
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3093321
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
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Cat. No. ABIN3136790
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Reactivity Mouse
Source Baculovirus infected Insect Cells, Insect cells (Sf9), Mouse
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Cat. No. ABIN6700238
Quantity 50 μg
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Latest Publications for our KDM4B Products

Xu, Moresco, Chang, Mukim, Smith, Diedrich, Yates, Jones: "SHMT2 and the BRCC36/BRISC deubiquitinase regulate HIV-1 Tat K63-ubiquitylation and destruction by autophagy." in: PLoS pathogens, Vol. 14, Issue 5, pp. e1007071, (2018) (PubMed).

Kim, Jung, Nagappan, Jung: "Histone H3K9 demethylase JMJD2B induces hepatic steatosis through upregulation of PPARγ2." in: Scientific reports, Vol. 8, Issue 1, pp. 13734, (2018) (PubMed).

Uribe, Buzzi, Bronner, Strobl-Mazzulla: "Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression." in: The Journal of cell biology, Vol. 211, Issue 4, pp. 815-27, (2015) (PubMed).

Mallette, Mattiroli, Cui, Young, Hendzel, Mer, Sixma, Richard: "RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites." in: The EMBO journal, Vol. 31, Issue 8, pp. 1865-78, (2012) (PubMed).

Toyokawa, Cho, Iwai, Yoshimatsu, Takawa, Hayami, Maejima, Shimizu, Tanaka, Tsunoda, Field, Kelly, Neal, Ponder, Maehara, Nakamura, Hamamoto: "The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6." in: Cancer prevention research (Philadelphia, Pa.), Vol. 4, Issue 12, pp. 2051-61, (2011) (PubMed).

Beyer, Kristensen, Jensen, Johansen, Staller: "The histone demethylases JMJD1A and JMJD2B are transcriptional targets of hypoxia-inducible factor HIF." in: The Journal of biological chemistry, Vol. 283, Issue 52, pp. 36542-52, (2008) (PubMed).

Synonyms and alternative names related to KDM4B

lysine demethylase 4B (KDM4B), lysine (K)-specific demethylase 4B (kdm4b), lysine (K)-specific demethylase 4B (KDM4B), lysine demethylase 4B (kdm4b), lysine (K)-specific demethylase 4B (Kdm4b), 4732474L06Rik, JMJD2B, jmjd2b, Jmjd2b, KDM4B, mKIAA0876, si:ch211-124a3.4, TDRD14B

Protein level used designations for KDM4B

  • lysine (K)-specific demethylase 4B
  • jumonji domain containing 2B
  • lysine-specific demethylase 4B
  • lysine-specific demethylase 4B-like
  • jmjC domain-containing histone demethylation protein 3B
  • jumonji domain-containing protein 2B
  • tudor domain containing 14B
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