KDELR2 产品
(KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 2 (KDELR2))
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Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. KDELR2 was the second member of the family to be identified, and it encodes a protein which is 83% identical to the KDELR1 gene product. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].
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Featured KDELR2 Categories
Recommended KDELR2 抗体
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Reactivity
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Cat. No.
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Datasheet
Reactivity
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Cat. No.
ABIN7187129
Quantity
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Datasheet
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Reactivity
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Cat. No.
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Recommended KDELR2 蛋白
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Tobacco (Nicotiana tabacum)
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Latest Publications for our KDELR2 Products
: "Mesencephalic astrocyte-derived neurotrophic factor (MANF) secretion and cell surface binding are modulated by KDEL receptors." in: The Journal of biological chemistry, Vol. 288, Issue 6, pp. 4209-25, (2013) (PubMed).Synonyms and alternative names related to KDELR2
KDEL endoplasmic reticulum protein retention receptor 2 L homeolog (kdelr2.L), KDEL endoplasmic reticulum protein retention receptor 2 (KDELR2), KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 (Kdelr2), KDEL endoplasmic reticulum protein retention receptor 2 (Kdelr2), KDEL endoplasmic reticulum protein retention receptor 1 L homeolog (kdelr1.L), 1110007A14Rik, ELP-1, ERD2.2, kdelr1-a, kdelr2Protein level used designations for KDELR2
- ER lumen protein retaining receptor 2
- KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- KDEL endoplasmic reticulum protein retention receptor 2
- KDEL receptor 2
- (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
- ERD-2-like protein
- ERD2-like protein 1
- ER lumen protein retaining receptor 1-A
- KDEL endoplasmic reticulum protein retention receptor 1-A
- KDEL receptor 1-A
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