KCNT1 产品
(Potassium Channel, Subfamily T, Member 1 (KCNT1))
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Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a sodium-activated potassium channel subunit which is thought to function in ion conductance and developmental signaling pathways. Mutations in this gene cause the early-onset epileptic disorders, malignant migrating partial seizures of infancy and autosomal dominant nocturnal frontal lobe epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012].
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Featured KCNT1 Categories
Recommended KCNT1 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC, AA
Validations
- (4)
Cat. No.
ABIN2482929
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC, AA
Validations
- (4)
Cat. No.
ABIN2482928
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IF, ICC, AA
Validations
- (4)
Cat. No.
ABIN2482927
Quantity
100 μg
Datasheet
Datasheet
Recommended KCNT1 蛋白
Product
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Human
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3115360
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135864
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNT1 Products
: "Slack channels expressed in sensory neurons control neuropathic pain in mice." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 35, Issue 3, pp. 1125-35, (2015) (PubMed).: "Identity, expression and functional role of the sodium-activated potassium current in vestibular ganglion afferent neurons." in: Neuroscience, Vol. 240, pp. 163-75, (2013) (PubMed).
: "TMEM16C facilitates Na(+)-activated K+ currents in rat sensory neurons and regulates pain processing." in: Nature neuroscience, Vol. 16, Issue 9, pp. 1284-90, (2013) (PubMed).
: "Regulation of neuronal excitability by interaction of fragile X mental retardation protein with slack potassium channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 44, pp. 15318-27, (2012) (PubMed).
: "SLO-2 is cytoprotective and contributes to mitochondrial potassium transport." in: PLoS ONE, Vol. 6, Issue 12, pp. e28287, (2011) (PubMed).
: "PKA-induced internalization of slack KNa channels produces dorsal root ganglion neuron hyperexcitability." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 30, Issue 42, pp. 14165-72, (2010) (PubMed).
: "The N-terminal domain of Slack determines the formation and trafficking of Slick/Slack heteromeric sodium-activated potassium channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 29, Issue 17, pp. 5654-65, (2009) (PubMed).
Synonyms and alternative names related to KCNT1
potassium sodium-activated channel subfamily T member 1 (KCNT1), potassium channel subfamily T member 1 (LOC100436526), potassium sodium-activated channel subfamily T member 1 (Kcnt1), potassium channel, subfamily T, member 1 (Kcnt1), potassium channel, sodium activated subfamily T, member 1 (kcnt1), bA100C15.2, C030030G16Rik, EIEE14, ENFL5, KCa4.1, MGC146594, mKIAA1422, rSlo2, SLACK, Slack, slack, slo2, Slo2.2Protein level used designations for KCNT1
- potassium channel subfamily T member 1
- potassium channel, subfamily T, member 1
- potassium channel subfamily T member 1-like
- potassium channel subunit (Slack)
- sequence like a calcium-activated potassium channel subunit
- sodium-activated potassium channel
- potassium channel subunit
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