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KCNQ3 产品

(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 3 (KCNQ3))

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The M channel is a slowly activating and deactivating potassium channel that plays a critical role in the regulation of neuronal excitability. The M channel is formed by the association of the protein encoded by this gene and one of two related proteins encoded by the KCNQ2 and KCNQ5 genes, both integral membrane proteins. M channel currents are inhibited by M1 muscarinic acetylcholine receptors and activated by retigabine, a novel anti-convulsant drug. Defects in this gene are a cause of benign familial neonatal convulsions type 2 (BFNC2), also known as epilepsy, benign neonatal type 2 (EBN2). Two variants encoding distinct isoforms have been found. [provided by RefSeq, Mar 2011].

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Featured KCNQ3 Categories

KCNQ3 抗体

High quality antibodies with extensive validation data.

Recommended KCNQ3 抗体

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Reactivity
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Datasheet
Reactivity Human
Application ELISA, WB, IF
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Cat. No. ABIN7164001
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Dog, Guinea Pig, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat
Application WB
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Cat. No. ABIN6746121
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Cat. No. ABIN2776162
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Recommended KCNQ3 蛋白

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Cat. No. ABIN3136578
Quantity 1 mg
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Reactivity Human
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Cat. No. ABIN3110095
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Latest Publications for our KCNQ3 Products

Ruan, Dietrich, Liu, Zimmer, Li, Singh, Zhang, Yin, Wu, Horvath, Yang: "O-GlcNAc transferase enables AgRP neurons to suppress browning of white fat." in: Cell, Vol. 159, Issue 2, pp. 306-17, (2014) (PubMed).

Ekberg, Schuetz, Boase, Conroy, Manning, Kumar, Poronnik, Adams: "Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2." in: The Journal of biological chemistry, Vol. 282, Issue 16, pp. 12135-42, (2007) (PubMed).

Synonyms and alternative names related to KCNQ3

potassium voltage-gated channel subfamily Q member 3 (KCNQ3), potassium voltage-gated channel, KQT-like subfamily, member 3 (kcnq3), potassium voltage-gated channel subfamily Q member 3 (Kcnq3), potassium voltage-gated channel, subfamily Q, member 3 (Kcnq3), BFNC2, EBN2, KCNQ3, KV7.3, si:ch211-66b9.3

Protein level used designations for KCNQ3

  • potassium voltage-gated channel, KQT-like subfamily, member 3
  • potassium voltage-gated channel KQT-like protein 3
  • potassium voltage-gated channel subfamily KQT member 3
  • potassium channel subunit alpha KvLQT3
  • potassium channel, voltage-gated, subfamily Q, member 3
  • voltage-gated potassium channel subunit Kv7.3
  • KQT-like 3
  • potassium voltage-gated channel, subfamily Q, member 3
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