KCNQ1 产品
(Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))
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This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011].
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Recommended KCNQ1 抗体
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Reactivity
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Human
Application
WB, IHC, IP, ICC, IF, AA
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- (5)
Cat. No.
ABIN361766
Quantity
100 μg
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Datasheet
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Human
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- (5)
Cat. No.
ABIN2483167
Quantity
100 μg
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Cat. No.
ABIN2483166
Quantity
100 μg
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Recommended KCNQ1 蛋白
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Tobacco (Nicotiana tabacum)
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ABIN3134696
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1 mg
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Reactivity
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Source
Tobacco (Nicotiana tabacum)
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Latest Publications for our KCNQ1 Products
: "Telmisartan cardioprotects from the ischaemic/hypoxic damage through a miR-1-dependent pathway." in: Journal of cellular and molecular medicine, Vol. 23, Issue 10, pp. 6635-6645, (2020) (PubMed).: "K(V)7.4 channels participate in the control of rodent renal vascular resting tone." in: Acta physiologica (Oxford, England), Vol. 214, Issue 3, pp. 402-14, (2015) (PubMed).
: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).
: "Synergistic restoring effects of isoproterenol and magnesium on KCNQ1-inhibited bradycardia cell models cultured in microelectrode array." in: Cardiology, Vol. 128, Issue 1, pp. 15-24, (2014) (PubMed).
: "BACE1 and presenilin/?-secretase regulate proteolytic processing of KCNE1 and 2, auxiliary subunits of voltage-gated potassium channels." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 27, Issue 6, pp. 2458-67, (2013) (PubMed).
: "Functional effects of KCNQ K(+) channels in airway smooth muscle." in: Frontiers in physiology, Vol. 4, pp. 277, (2013) (PubMed).
: "Single-channel basis for the slow activation of the repolarizing cardiac potassium current, I(Ks)." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 11, pp. E996-1005, (2013) (PubMed).
: "Deubiquitylating enzyme USP2 counteracts Nedd4-2-mediated downregulation of KCNQ1 potassium channels." in: Heart rhythm : the official journal of the Heart Rhythm Society, Vol. 9, Issue 3, pp. 440-8, (2012) (PubMed).
: "Mechanistic basis for LQT1 caused by S3 mutations in the KCNQ1 subunit of IKs." in: The Journal of general physiology, Vol. 135, Issue 5, pp. 433-48, (2010) (PubMed).
: "Dynamic partnership between KCNQ1 and KCNE1 and influence on cardiac IKs current amplitude by KCNE2." in: The Journal of biological chemistry, Vol. 284, Issue 24, pp. 16452-62, (2009) (PubMed).
Synonyms and alternative names related to KCNQ1
potassium voltage-gated channel subfamily Q member 1 (KCNQ1), KCNQ potassium channel (KCNQ), potassium voltage-gated channel, KQT-like subfamily, member 1 (KCNQ1), potassium channel, voltage gated KQT-like subfamily Q, member 1 (kcnq1), voltage gated potassium channel subunit (kcnq1), potassium voltage-gated channel subfamily Q member 1 (Kcnq1), potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog (kcnq1.L), potassium voltage-gated channel, KQT-like subfamily, member 1 (kcnq1), potassium voltage-gated channel, subfamily Q, member 1 (Kcnq1), ATFB1, ATFB3, AW559127, CG12215, CG12915, CG33135, DKCNQ, dKCNQ, Dmel\\CG33135, JLNS1, KCNA8, KCNA9, Kcna9, kcnq1, KCNQ1, kcnq1-A, kqt-3, Kv1.9, Kv7.1, kv7.1, KvLQT-1, KVLQT1, Kvlqt1, KvLQT1, LQT, LQT1, RWS, SQT2, WRS, xkvlqt1, zgc:158384Protein level used designations for KCNQ1
- IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1
- kidney and cardiac voltage dependend K+ channel
- potassium voltage-gated channel subfamily KQT member 1
- slow delayed rectifier channel subunit
- voltage-gated potassium channel subunit Kv7.1
- CG33135-PC
- CG33135-PD
- CG33135-PE
- CG33135-PF
- CG33135-PG
- CG33135-PH
- CG33135-PI
- CG33135-PJ
- CG33135-PK
- KCNQ-PC
- KCNQ-PD
- KCNQ-PE
- KCNQ-PF
- KCNQ-PG
- KCNQ-PH
- KCNQ-PI
- KCNQ-PJ
- KCNQ-PK
- KCNQ-type K[+] channel
- Potassium voltage-gated channel subfamily KQT member 1
- potassium channel protein (KvLQT1)
- ventricular voltage-gated K+ channel pore-forming subunit KCNQ1
- KvLQT1 voltage-gated delayed rectifier potassium channel
- potassium voltage-gated channel, KQT-like subfamily, member 1
- potassium channel protein KCNQ1
- potassium voltage-gated channel, subfamily Q, member 1
- voltage gated potassium channel subunit
- KQT-like 1
- IKs producing slow voltage-gated potassium channel subunit alpha xKvLQT1
- Voltage-gated potassium channel subunit Kv7.1
- potassium channel protein
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