KCNN3 产品
(Small Conductance Calcium-Activated Potassium Channel Protein 3 (KCNN3))
Categories
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011].
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Featured KCNN3 Categories
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Recommended KCNN3 ELISA试剂盒
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Recommended KCNN3 蛋白
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Latest Publications for our KCNN3 Products
: "Altered distribution of small-conductance calcium-activated potassium channel SK3 in Hirschsprung's disease." in: Journal of pediatric surgery, Vol. 50, Issue 10, pp. 1659-64, (2015) (PubMed).Synonyms and alternative names related to KCNN3
potassium calcium-activated channel subfamily N member 3 (Kcnn3), potassium calcium-activated channel subfamily N member 3 (KCNN3), potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3 (Kcnn3), hSK3, KCa2.3, SK3, SKCA3Protein level used designations for KCNN3
- SKCa 3
- SKCa3
- small conductance calcium-activated potassium channel protein 3
- small-conductance Ca2+-activated K+ channel 3
- SK3
- calcium activated potassium channel SK3
- small conductance calcium-activated potassium channel 3
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