KCNJ2 产品
(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 2 (KCNJ2))
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Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Mutations in this gene have been associated with Andersen syndrome, which is characterized by periodic paralysis, cardiac arrhythmias, and dysmorphic features. [provided by RefSeq, Jul 2008].
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Recommended KCNJ2 抗体
Product
Reactivity
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Quantity
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Reactivity
Mouse
Application
WB, IHC, ICC, IF, AA
Validations
- (5)
Cat. No.
ABIN361769
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IF, AA
Validations
- (4)
Cat. No.
ABIN2483541
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, ICC, IF, AA
Validations
- (4)
Cat. No.
ABIN2483540
Quantity
100 μg
Datasheet
Datasheet
Recommended KCNJ2 蛋白
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Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308447
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our KCNJ2 Products
: "Reversible Dilated Cardiomyopathy Caused by a High Burden of Ventricular Arrhythmias in Andersen-Tawil Syndrome." in: The Canadian journal of cardiology, Vol. 32, Issue 12, pp. 1576.e15-1576.e18, (2016) (PubMed).: "Inward rectifier potassium currents in mammalian skeletal muscle fibres." in: The Journal of physiology, Vol. 593, Issue 5, pp. 1213-38, (2015) (PubMed).
: "Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart." in: Journal of molecular and cellular cardiology, Vol. 86, pp. 85-94, (2015) (PubMed).
: "Rise and Fall of Kir2.2 Current by TLR4 Signaling in Human Monocytes: PKC-Dependent Trafficking and PI3K-Mediated PIP2 Decrease." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 7, pp. 3345-54, (2015) (PubMed).
: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).
: "PDZ domain-binding motif regulates cardiomyocyte compartment-specific NaV1.5 channel expression and function." in: Circulation, Vol. 130, Issue 2, pp. 147-60, (2014) (PubMed).
: "MicroRNA-26 governs profibrillatory inward-rectifier potassium current changes in atrial fibrillation." in: The Journal of clinical investigation, Vol. 123, Issue 5, pp. 1939-51, (2013) (PubMed).
: "Striatal D2 receptors regulate dendritic morphology of medium spiny neurons via Kir2 channels." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 32, Issue 7, pp. 2398-409, (2012) (PubMed).
: "Dynamic reciprocity of sodium and potassium channel expression in a macromolecular complex controls cardiac excitability and arrhythmia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 109, Issue 31, pp. E2134-43, (2012) (PubMed).
: "ST depression, arrhythmia, vagal dominance, and reduced cardiac micro-RNA in particulate-exposed rats." in: American journal of respiratory cell and molecular biology, Vol. 44, Issue 2, pp. 185-96, (2011) (PubMed).
Synonyms and alternative names related to KCNJ2
potassium voltage-gated channel subfamily J member 2 (KCNJ2), potassium voltage-gated channel subfamily J member 2 (Kcnj2), potassium inwardly-rectifying channel, subfamily J, member 2 (Kcnj2), ATFB9, HHBIRK1, HHIRK1, IRK-1, IRK1, Kcnf1, KCNJ2, KIR2.1, Kir2.1, LQT7, SQT3Protein level used designations for KCNJ2
- IRK-1
- inward rectifier K(+) channel Kir2.1
- inward rectifier potassium channel 2
- potassium channel, inwardly rectifying subfamily J member 2
- cardiac inward rectifier potassium channel
- hIRK1
- inward rectifier K+ channel KIR2.1
- RBL-IRK1
- BIK
- inward rectifier potassium channel cIRK1
- cardiac inward rectifier KIR2.1
- inwardly rectifying potassium channel Kir2.1
- inward rectifier potassium channel Kir2.1
- inwardly-rectifying potassium channel Kir2.1
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