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KCNJ11 产品

(Potassium Inwardly-Rectifying Channel, Subfamily J, Member 11 (KCNJ11))
Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins and is found associated with the sulfonylurea receptor SUR. Mutations in this gene are a cause of familial persistent hyperinsulinemic hypoglycemia of infancy (PHHI), an autosomal recessive disorder characterized by unregulated insulin secretion. Defects in this gene may also contribute to autosomal dominant non-insulin-dependent diabetes mellitus type II (NIDDM), transient neonatal diabetes mellitus type 3 (TNDM3), and permanent neonatal diabetes mellitus (PNDM). Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Oct 2009].

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Featured KCNJ11 Categories

KCNJ11 抗体

High quality antibodies with extensive validation data.

KCNJ11 ELISA试剂盒

Reliable ELISA kits for a wide range of species.

KCNJ11 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNJ11 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7145021
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (2)
Cat. No. ABIN561585
Quantity 50 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN238541
Quantity 100 μg
Datasheet Datasheet

Recommended KCNJ11 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380468
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended KCNJ11 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308438
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308437
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3114863
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCNJ11 Products

Filosa, Bonev, Straub, Meredith, Wilkerson, Aldrich, Nelson: "Local potassium signaling couples neuronal activity to vasodilation in the brain." in: Nature neuroscience, Vol. 9, Issue 11, pp. 1397-1403, (2006) (PubMed).

Synonyms and alternative names related to KCNJ11

potassium voltage-gated channel subfamily J member 11 (KCNJ11), potassium inwardly-rectifying channel, subfamily J, member 11 (kcnj11), potassium inwardly rectifying channel, subfamily J, member 11 (Kcnj11), potassium voltage-gated channel subfamily J member 11 (Kcnj11), BIR, HHF2, IKATP, kir6.2, Kir6.2, KIR6.2, mBIR, PHHI, TNDM3

Protein level used designations for KCNJ11

  • potassium inwardly-rectifying channel, subfamily J, member 11
  • potassium inwardly-rectifying channel J11
  • ATP-sensitive inward rectifier potassium channel 11
  • ATP-sensitive inward rectifier potassium channel 11-like
  • inward rectifier K(+) channel Kir6.2
  • BIR
  • potassium channel, inwardly rectifying subfamily J member 11
  • potassium inwardly-rectifying channel subfamily J member 11
  • IKATP
  • inward rectifier potassium channel Kir6.2
  • beta-cell inward rectifier subunit
  • inwardly rectifying potassium channel KIR6.2
  • potassium channel inwardly rectifing subfamily J member 11
  • potassium inwardly rectifying channel, subfamily J, member 11
  • ATP-sensitive inward rectifier potassium channel Kir6.2
  • inwardly rectifying potassium channel Kir6.2
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