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KCNIP2 产品

(Kv Channel Interacting Protein 2 (KCNIP2))

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This gene encodes a member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belongs to the recoverin branch of the EF-hand superfamily. Members of the KCNIP family are small calcium binding proteins. They all have EF-hand-like domains, and differ from each other in the N-terminus. They are integral subunit components of native Kv4 channel complexes. They may regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified from this gene. [provided by RefSeq, Jul 2008].

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KCNIP2 抗体

High quality antibodies with extensive validation data.

KCNIP2 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCNIP2 抗体

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Cat. No. ABIN2776321
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Cat. No. ABIN565469
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Cat. No. ABIN7456223
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Latest Publications for our KCNIP2 Products

Isensee, Wenzel, Buschow, Weissmann, Kuss, Hucho: "Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit." in: PLoS ONE, Vol. 9, Issue 12, pp. e115731, (2015) (PubMed).

You, Mao, Cai, Li, Xu: "Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 309-15, (2015) (PubMed).

El Gebeily, El Khoury, Mathieu, Brouillette, Fiset: "Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart." in: Journal of molecular and cellular cardiology, Vol. 86, pp. 85-94, (2015) (PubMed).

Rudakova, Wagner, Frank, Volk: "Localization of Kv4.2 and KChIP2 in lipid rafts and modulation of outward K+ currents by membrane cholesterol content in rat left ventricular myocytes." in: Pflügers Archiv : European journal of physiology, Vol. 467, Issue 2, pp. 299-309, (2015) (PubMed).

Foeger, Wang, Mellor, Nerbonne: "Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents." in: The Journal of physiology, Vol. 591, Issue Pt 17, pp. 4149-66, (2014) (PubMed).

Lopez-Izquierdo, Pereira, Wende, Punske, Abel, Tristani-Firouzi: "The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization." in: American journal of physiology. Heart and circulatory physiology, Vol. 306, Issue 5, pp. H747-54, (2014) (PubMed).

Lei, Zhang, Liang, Cui, Xu, Xu: "Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats." in: Journal of neuroscience research, Vol. 92, Issue 12, pp. 1775-84, (2014) (PubMed).

Rainnie, Hazra, Dabrowska, Guo, Li, Dewitt, Muly: "Distribution and functional expression of Kv4 family ? subunits and associated KChIP ? subunits in the bed nucleus of the stria terminalis." in: The Journal of comparative neurology, Vol. 522, Issue 3, pp. 609-25, (2013) (PubMed).

Speerschneider, Grubb, Metoska, Olesen, Calloe, Thomsen: "Development of heart failure is independent of K+ channel-interacting protein 2 expression." in: The Journal of physiology, Vol. 591, Issue Pt 23, pp. 5923-37, (2013) (PubMed).

Mercer, Ma, Watts, Strome, Wohlgemuth, Yang, Cashman, Coulthart, Schmitt-Ulms, Jhamandas, Westaway: "The prion protein modulates A-type K+ currents mediated by Kv4.2 complexes through dipeptidyl aminopeptidase-like protein 6." in: The Journal of biological chemistry, Vol. 288, Issue 52, pp. 37241-55, (2013) (PubMed).

Synonyms and alternative names related to KCNIP2

potassium voltage-gated channel interacting protein 2 (KCNIP2), Kv channel-interacting protein 2 (Kcnip2), Kv channel interacting protein 2 S homeolog (kcnip2.S), potassium voltage-gated channel interacting protein 2 (Kcnip2), Kv channel interacting protein 2 (kcnip2), KCHIP2, Kchip2, KChIP2, kchip2, KCNIP2, si:ch73-173h19.2

Protein level used designations for KCNIP2

  • A-type potassium channel modulatory protein 2
  • Kv channel-interacting protein 2
  • cardiac voltage-gated potassium channel modulatory subunit
  • potassium channel-interacting protein 2
  • Kv channel interacting protein 2
  • potassium channel auxiliary subunit KCHIP2
  • Kv channel-interacting protein
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