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KCND3 产品

(Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 3 (KCND3))

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Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shal-related subfamily, members of which form voltage-activated A-type potassium ion channels and are prominent in the repolarization phase of the action potential. This member includes two isoforms with different sizes, which are encoded by alternatively spliced transcript variants of this gene. [provided by RefSeq, Jul 2008].

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Featured KCND3 Categories

KCND3 抗体

High quality antibodies with extensive validation data.

KCND3 蛋白

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended KCND3 抗体

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN7262833
Quantity 200 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (2)
Cat. No. ABIN6142701
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (1)
Cat. No. ABIN7129956
Quantity 100 μL
Datasheet Datasheet

Recommended KCND3 ELISA试剂盒

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6969459
Quantity 96 tests
Datasheet Datasheet

Recommended KCND3 蛋白

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1330256
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3118988
Quantity 1 mg
Datasheet Datasheet
Reactivity Mouse
Source Tobacco (Nicotiana tabacum)
Validations
Cat. No. ABIN3120244
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our KCND3 Products

Duarri, Lin, Fokkens, Meijer, Smeets, Nibbeling, Boddeke, Sinke, Kampinga, Papazian, Verbeek: "Spinocerebellar ataxia type 19/22 mutations alter heterocomplex Kv4.3 channel function and gating in a dominant manner." in: Cellular and molecular life sciences : CMLS, Vol. 72, Issue 17, pp. 3387-99, (2015) (PubMed).

Cheng, Cheng, Chen, Rau, Chang, Tsaur: "NGF-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain." in: Pain, (2015) (PubMed).

Liu, Kim, Morales, Heximer, Hui, Backx: "Kv4.3-Encoded Fast Transient Outward Current Is Presented in Kv4.2 Knockout Mouse Cardiomyocytes." in: PLoS ONE, Vol. 10, Issue 7, pp. e0133274, (2015) (PubMed).

You, Mao, Cai, Li, Xu: "Two novel Brugada syndrome-associated mutations increase KV4.3 membrane expression and function." in: International journal of molecular medicine, Vol. 36, Issue 1, pp. 309-15, (2015) (PubMed).

Zhao, Xu, Yun, Zhao, Li, Gong, Yuan, Yan, Zhang, Ding, Wang, Zhang, Dong, Xiu, Yang, Liu, Xue, Li: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).

Dufour, Woodhouse, Goaillard: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).

Lei, Zhang, Liang, Cui, Xu, Xu: "Reduced expression of IA channels is associated with postischemic seizures in hyperglycemic rats." in: Journal of neuroscience research, Vol. 92, Issue 12, pp. 1775-84, (2014) (PubMed).

Duarri, Jezierska, Fokkens, Meijer, Schelhaas, den Dunnen, van Dijk, Verschuuren-Bemelmans, Hageman, van de Vlies, Küsters, van de Warrenburg, Kremer, Wijmenga, Sinke, Swertz, Kampinga, Boddeke et al.: "Mutations in potassium channel kcnd3 cause spinocerebellar ataxia type 19. ..." in: Annals of neurology, Vol. 72, Issue 6, pp. 870-80, (2013) (PubMed).

David, Andersen, Olesen, Rasmussen, Schmitt: "Trafficking of the IKs -complex in MDCK cells: site of subunit assembly and determinants of polarized localization." in: Traffic (Copenhagen, Denmark), Vol. 14, Issue 4, pp. 399-411, (2013) (PubMed).

Duarri, Nibbeling, Fokkens, Meijer, Boddeke, Lagrange, Stevanin, Brice, Durr, Verbeek: "The L450P mutation in KCND3 brings spinocerebellar ataxia and Brugada syndrome closer together." in: Neurogenetics, Vol. 14, Issue 3-4, pp. 257-8, (2013) (PubMed).

Synonyms and alternative names related to KCND3

potassium voltage-gated channel subfamily D member 3 (KCND3), potassium voltage-gated channel subfamily D member 3 (kcnd3), potassium voltage-gated channel, Shal-related subfamily, member 3 (kcnd3), potassium channel, voltage gated Shal related subfamily D, member 3 (kcnd3), potassium voltage-gated channel, Shal-related family, member 3 (Kcnd3), potassium voltage-gated channel subfamily D member 3 (Kcnd3), potassium channel, voltage gated Shal related subfamily D, member 3 L homeolog (kcnd3.L), AW045978, K(v)4.3, KCND3, kcnd3-A, KCND3L, KCND3S, Kncd3, KSHIVB, kv4.3, Kv4.3, KV4.3, wu:fi06g01, xKv4.3, zgc:55306

Protein level used designations for KCND3

  • potassium voltage-gated channel, Shal-related subfamily, member 3
  • potassium voltage-gated channel subfamily D member 3-like
  • potassium voltage-gated channel subfamily D member 3
  • potassium voltage-gated channel, Shal-related family, member 3
  • zShal3
  • potassium channel Kv4.3
  • potassium voltage-gated channel Shal-related subfamily member 3
  • potassium channel Kv4.3L
  • potassium channel Kv4.3M
  • voltage-gated potassium channel subunit Kv4.3
  • potassium ionic channel Kv4.3
  • sha1-related potassium channel Kv4.3
  • voltage-gated K+ channel
  • potassium voltage gated channel, Shal-related family, member 3
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