KCNA5 产品
(Potassium Voltage-Gated Channel, Shaker-Related Subfamily, Member 5 (KCNA5))
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Potassium channels represent the most complex class of voltage-gated ino channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class, the function of which could restore the resting membrane potential of beta cells after depolarization and thereby contribute to the regulation of insulin secretion. This gene is intronless, and the gene is clustered with genes KCNA1 and KCNA6 on chromosome 12. Defects in this gene are a cause of familial atrial fibrillation type 7 (ATFB7). [provided by RefSeq, May 2012].
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Featured KCNA5 Categories
Recommended KCNA5 抗体
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC, IF, ICC
Validations
- (2)
Cat. No.
ABIN6257764
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Monkey
Application
WB
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- (1)
Cat. No.
ABIN6746072
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Rat
Application
WB, IHC, IF, ICC, FACS
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- (3)
Cat. No.
ABIN7043529
Quantity
25 μL
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Recommended KCNA5 ELISA试剂盒
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6969458
Quantity
96 tests
Datasheet
Datasheet
Recommended KCNA5 蛋白
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Reactivity
Source
Validations
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Datasheet
Reactivity
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Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3113177
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Mouse
Source
Tobacco (Nicotiana tabacum)
Validations
Cat. No.
ABIN3135457
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our KCNA5 Products
: "Selective down-regulation of KV2.1 function contributes to enhanced arterial tone during diabetes." in: The Journal of biological chemistry, Vol. 290, Issue 12, pp. 7918-29, (2015) (PubMed).: "Estrogen regulation of the transient outward K(+) current involves estrogen receptor α in mouse heart." in: Journal of molecular and cellular cardiology, Vol. 86, pp. 85-94, (2015) (PubMed).
: "Chronic obstructive sleep apnea causes atrial remodeling in canines: mechanisms and implications." in: Basic research in cardiology, Vol. 109, Issue 5, pp. 427, (2014) (PubMed).
: "The absence of insulin signaling in the heart induces changes in potassium channel expression and ventricular repolarization." in: American journal of physiology. Heart and circulatory physiology, Vol. 306, Issue 5, pp. H747-54, (2014) (PubMed).
: "Deletion of the Kv2.1 delayed rectifier potassium channel leads to neuronal and behavioral hyperexcitability." in: Genes, brain, and behavior, Vol. 13, Issue 4, pp. 394-408, (2014) (PubMed).
: "Somatodendritic ion channel expression in substantia nigra pars compacta dopaminergic neurons across postnatal development." in: Journal of neuroscience research, Vol. 92, Issue 8, pp. 981-99, (2014) (PubMed).
: "Novel objective classification of reactive microglia following hypoglossal axotomy using hierarchical cluster analysis." in: The Journal of comparative neurology, Vol. 521, Issue 5, pp. 1184-201, (2013) (PubMed).
: "A defined heteromeric KV1 channel stabilizes the intrinsic pacemaking and regulates the output of deep cerebellar nuclear neurons to thalamic targets." in: The Journal of physiology, Vol. 591, Issue Pt 7, pp. 1771-91, (2013) (PubMed).
: "Contribution of Kv1.2 voltage-gated potassium channel to D2 autoreceptor regulation of axonal dopamine overflow." in: The Journal of biological chemistry, Vol. 286, Issue 11, pp. 9360-72, (2011) (PubMed).
: "Characterization of ion channels involved in the proliferative response of femoral artery smooth muscle cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 30, Issue 6, pp. 1203-11, (2010) (PubMed).
Synonyms and alternative names related to KCNA5
potassium voltage-gated channel subfamily A member 5 (KCNA5), potassium channel, voltage gated shaker related subfamily A, member 5 (kcna5), potassium voltage-gated channel, shaker-related subfamily, member 5 (Kcna5), potassium voltage-gated channel subfamily A member 5 (Kcna5), ATFB7, HCK1, HK2, HPCN1, KCNA5, kcna5, Kv1, KV1.5, Kv1.5, PCN1Protein level used designations for KCNA5
- potassium voltage-gated channel, shaker-related subfamily, member 5
- potassium voltage-gated channel subfamily A member 5-like
- cardiac potassium channel
- insulinoma and islet potassium channel
- potassium channel 1
- potassium voltage-gated channel subfamily A member 5
- voltage-gated potassium channel HK2
- voltage-gated potassium channel protein Kv1.5
- voltage-gated potassium channel subunit Kv1.5
- KV1-5
- Potassium (K+) channel protein alpha 5
- RCK7
- RK4
- potassium voltage gated channel, shaker related subfamily, member 5
- shaker subfamily potassium channel Kv1.5 alpha subunit
- delayed rectifier K+ channel
- Kv1.5 potassium channel
- potassium voltage-gated channel shaker-related subfamily member 5
- potassium voltage-gated channel shaker-related subfamily 5
- potassium channel Kv1.5
- voltage-gated potassium channel Kv1.5
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